LOW-VOLUME · HOSP-HEAVY
tranylcypromine Side Effects
tranylcypromine (also sold as Parnate) is a LOW-VOLUME FAERS extract #511 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 35.3% mention hospitalization (116 reports).
Data updated 2026-05-15
- 329
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
tranylcypromine: 35.3% mention hospitalization (116 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #511 of 524 by FAERS report count.
Thinner FAERS extract for tranylcypromine (Parnate) (329 reports #511 of 524 by FAERS report count). 35.3% mention hospitalization (116 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG INTERACTION leads 68 of 329 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (86 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (49 reports, 14.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 18 |
| DYSMORPHISM | 12 |
| ATRIOVENTRICULAR SEPTAL DEFECT | 11 |
| FOETAL EXPOSURE DURING PREGNANCY | 10 |
| DRUG INTERACTION | 9 |
| FOETAL DEATH | 8 |
| HYPERTHERMIA | 7 |
| SEROTONIN SYNDROME | 7 |
| TOXICITY TO VARIOUS AGENTS | 7 |
| HYPERTELORISM OF ORBIT | 6 |
| RESPIRATORY ARREST | 6 |
| RHABDOMYOLYSIS | 6 |
| ACIDOSIS | 5 |
| MYOCLONUS | 5 |
| PLACENTAL INFARCTION | 5 |
| CONTRAINDICATED PRODUCT ADMINISTERED | 4 |
| DEATH | 4 |
| DRUG DOSE TITRATION NOT PERFORMED | 4 |
| HAEMORRHAGE INTRACRANIAL | 4 |
| HYPOTENSION | 4 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (116, 35.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DRUG INTERACTION | 20 |
| DEPRESSION | 18 |
| SEROTONIN SYNDROME | 14 |
| HYPERTENSION | 13 |
| HYPERTENSIVE CRISIS | 13 |
| BLOOD PRESSURE FLUCTUATION | 12 |
| CONTRAINDICATED PRODUCT ADMINISTERED | 11 |
| OVERDOSE | 11 |
| COMPLETED SUICIDE | 10 |
| HEADACHE | 10 |
| HYPERTHERMIA | 10 |
| PARAESTHESIA | 10 |
| POTENTIATING DRUG INTERACTION | 10 |
| SUICIDAL IDEATION | 10 |
| ABDOMINAL DISTENSION | 9 |
| MUSCULAR WEAKNESS | 9 |
| PRESCRIBED OVERDOSE | 9 |
| THERAPEUTIC RESPONSE UNEXPECTED | 9 |
How to read tranylcypromine FAERS figures (TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 329 voluntary reports linked to tranylcypromine (Parnate), 2004-2025. Death is listed on 49 (14.9%). Hospitalization appears on 116 (35.3%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with tranylcypromine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 318 FAERS cases (Δ 11 lighter vs tranylcypromine); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 299 FAERS cases (Δ 30 lighter vs tranylcypromine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 278 FAERS cases (Δ 51 lighter vs tranylcypromine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 408 FAERS cases (Δ 79 heavier vs tranylcypromine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 47.2 pp vs tranylcypromine's DEATH-HEAVY): CASELOAD · HOSP-MID.
tranylcypromine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload TRACE-CASE and the label guide.