LOW-VOLUME · HOSP-HEAVY
leuprolide Side Effects
leuprolide (also sold as Lupron) is a LOW-VOLUME FAERS extract #478 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 33.0% mention hospitalization (457 reports).
Data updated 2026-05-15
- 1,385
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
leuprolide: 33.0% mention hospitalization (457 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #478 of 524 by FAERS report count.
Thinner FAERS extract for leuprolide (Lupron) (1,385 reports #478 of 524 by FAERS report count). 33.0% mention hospitalization (457 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2005–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 82 of 1,385 reports
Who reports · age peak 65-74 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 65-74 (268 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (119 reports, 8.6%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 29 |
| MALIGNANT NEOPLASM PROGRESSION | 16 |
| ACUTE KIDNEY INJURY | 10 |
| ANAEMIA | 10 |
| METASTASES TO BONE | 9 |
| PNEUMONIA | 8 |
| PROSTATE CANCER | 8 |
| HYPOTENSION | 7 |
| DISEASE PROGRESSION | 6 |
| FATIGUE | 6 |
| FEBRILE NEUTROPENIA | 6 |
| METASTASES TO LIVER | 6 |
| PNEUMOCYSTIS JIROVECII PNEUMONIA | 6 |
| RESPIRATORY FAILURE | 6 |
| DYSPNOEA | 5 |
| FALL | 5 |
| GASTROENTERITIS NOROVIRUS | 5 |
| OPHTHALMIC HERPES ZOSTER | 5 |
| PAIN | 5 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (457, 33.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| FEBRILE NEUTROPENIA | 37 |
| NAUSEA | 27 |
| ACUTE KIDNEY INJURY | 26 |
| FATIGUE | 26 |
| VOMITING | 24 |
| ANAEMIA | 22 |
| FALL | 20 |
| HYPOTENSION | 19 |
| THROMBOCYTOPENIA | 19 |
| MALIGNANT NEOPLASM PROGRESSION | 18 |
| ASTHENIA | 17 |
| DRUG DEPENDENCE | 17 |
| DYSPNOEA | 17 |
| HYPERTENSION | 17 |
| INTENTIONAL PRODUCT MISUSE | 17 |
| RESPIRATORY DEPRESSION | 17 |
| DIARRHOEA | 16 |
| PNEUMOCYSTIS JIROVECII PNEUMONIA | 16 |
How to read leuprolide FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 1,385 voluntary reports linked to leuprolide (Lupron), 2005-2025. Death is listed on 119 (8.6%). Hospitalization appears on 457 (33.0%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with leuprolide
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 1,388 FAERS cases (Δ 3 heavier vs leuprolide); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,302 FAERS cases (Δ 83 lighter vs leuprolide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,476 FAERS cases (Δ 91 heavier vs leuprolide); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,480 FAERS cases (Δ 95 heavier vs leuprolide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.5 pp vs leuprolide's DEATH-HEAVY): CASELOAD · HOSP-MID.
leuprolide stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.