HIGH-VOLUME · HOSP-HEAVY
hydrocortisone Side Effects
hydrocortisone (also sold as Cortef) is HIGH-VOLUME in this FAERS book #89 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 40.6% mention hospitalization (34,415 reports).
Data updated 2026-05-15
- 84,725
- FAERS reports
FAERS voluntary reports, 2001 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
hydrocortisone: 40.6% mention hospitalization (34,415 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #89 of 524 by FAERS report count.
High-report extract for hydrocortisone (Cortef): 84,725 FAERS rows (2001-2025). Top named reactions: FATIGUE, PAIN, CONDITION AGGRAVATED. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2001–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 8,851 of 84,725 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (17,968 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (10,868 reports, 12.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,881 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 1,697 |
| FATIGUE | 1,673 |
| VOMITING | 1,551 |
| CONDITION AGGRAVATED | 1,525 |
| RASH | 1,510 |
| PNEUMONIA | 1,503 |
| DIARRHOEA | 1,496 |
| HYPERTENSION | 1,493 |
| SYSTEMIC LUPUS ERYTHEMATOSUS | 1,490 |
| INFUSION RELATED REACTION | 1,485 |
| DYSPNOEA | 1,462 |
| WOUND | 1,460 |
| TYPE 2 DIABETES MELLITUS | 1,454 |
| SWELLING | 1,446 |
| PAIN | 1,432 |
| GLOSSODYNIA | 1,429 |
| RHEUMATOID ARTHRITIS | 1,393 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (34,415, 40.6% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| FATIGUE | 3,951 |
| DIARRHOEA | 3,457 |
| DYSPNOEA | 3,444 |
| NAUSEA | 3,431 |
| PYREXIA | 3,393 |
| PAIN | 3,325 |
| VOMITING | 3,233 |
| ARTHRALGIA | 3,066 |
| HEADACHE | 2,967 |
| CONDITION AGGRAVATED | 2,933 |
| PNEUMONIA | 2,785 |
| MALAISE | 2,743 |
| RASH | 2,702 |
| ASTHENIA | 2,403 |
| INFUSION RELATED REACTION | 2,273 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 2,267 |
| HYPERTENSION | 2,258 |
| WEIGHT INCREASED | 2,196 |
How to read hydrocortisone FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 84,725 voluntary reports linked to hydrocortisone (Cortef), 2001-2025. Death is listed on 10,868 (12.8%). Hospitalization appears on 34,415 (40.6%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with hydrocortisone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 85,635 FAERS cases (Δ 910 heavier vs hydrocortisone); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 83,781 FAERS cases (Δ 944 lighter vs hydrocortisone); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 83,476 FAERS cases (Δ 1,249 lighter vs hydrocortisone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 82,622 FAERS cases (Δ 2,103 lighter vs hydrocortisone); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.3 pp vs hydrocortisone's DEATH-HEAVY): CASELOAD · HOSP-MID.
hydrocortisone stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.