LOW-VOLUME · HOSP-HEAVY
fidaxomicin Side Effects
fidaxomicin (also sold as Dificid) is a LOW-VOLUME FAERS extract #449 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 30.8% mention hospitalization (699 reports).
Data updated 2026-05-15
- 2,273
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
fidaxomicin: 30.8% mention hospitalization (699 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #449 of 524 by FAERS report count.
Thinner FAERS extract for fidaxomicin (Dificid) (2,273 reports #449 of 524 by FAERS report count). 30.8% mention hospitalization (699 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2011–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
CLOSTRIDIUM DIFFICILE INFECTION leads 461 of 2,273 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (422 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (248 reports, 10.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 69 |
| CLOSTRIDIUM DIFFICILE INFECTION | 45 |
| DIARRHOEA | 29 |
| SEPTIC SHOCK | 28 |
| SEPSIS | 25 |
| RESPIRATORY FAILURE | 24 |
| DYSPNOEA | 20 |
| ANAEMIA | 18 |
| CLOSTRIDIUM DIFFICILE COLITIS | 18 |
| HYPOXIA | 18 |
| MELAENA | 18 |
| PYREXIA | 18 |
| MALAISE | 17 |
| CHEST PAIN | 16 |
| CHILLS | 16 |
| GASTROENTERITIS | 16 |
| PATHOGEN RESISTANCE | 16 |
| DRUG RESISTANCE | 14 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (699, 30.8% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| CLOSTRIDIUM DIFFICILE INFECTION | 191 |
| DIARRHOEA | 123 |
| CLOSTRIDIUM DIFFICILE COLITIS | 82 |
| PYREXIA | 55 |
| NAUSEA | 53 |
| DISEASE RECURRENCE | 51 |
| ACUTE KIDNEY INJURY | 41 |
| VOMITING | 37 |
| SEPSIS | 36 |
| SEPTIC SHOCK | 34 |
| ANAEMIA | 33 |
| DYSPNOEA | 33 |
| RESPIRATORY FAILURE | 33 |
| ABDOMINAL PAIN | 31 |
| MALAISE | 30 |
| FATIGUE | 28 |
| CLOSTRIDIUM TEST POSITIVE | 27 |
| PANCYTOPENIA | 24 |
How to read fidaxomicin FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 2,273 voluntary reports linked to fidaxomicin (Dificid), 2011-2025. Death is listed on 248 (10.9%). Hospitalization appears on 699 (30.8%). Top co-reported indication: Clostridium Difficile Infection.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with fidaxomicin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 2,289 FAERS cases (Δ 16 heavier vs fidaxomicin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,254 FAERS cases (Δ 19 lighter vs fidaxomicin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,311 FAERS cases (Δ 38 heavier vs fidaxomicin); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 2,229 FAERS cases (Δ 44 lighter vs fidaxomicin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.2 pp vs fidaxomicin's DEATH-HEAVY): CASELOAD · HOSP-MID.
fidaxomicin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.