LOW-VOLUME · HOSP-HEAVY
disulfiram Side Effects
disulfiram (also sold as Antabuse) is a LOW-VOLUME FAERS extract #487 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 46.8% mention hospitalization (504 reports).
Data updated 2026-05-15
- 1,076
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
disulfiram: 46.8% mention hospitalization (504 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #487 of 524 by FAERS report count.
Thinner FAERS extract for disulfiram (Antabuse) (1,076 reports #487 of 524 by FAERS report count). 46.8% mention hospitalization (504 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG INTERACTION leads 120 of 1,076 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (393 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (111 reports, 10.3%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 19 |
| CARDIAC ARREST | 18 |
| COMPLETED SUICIDE | 18 |
| TOXICITY TO VARIOUS AGENTS | 16 |
| RESPIRATORY ARREST | 12 |
| CARDIO-RESPIRATORY ARREST | 10 |
| LACTIC ACIDOSIS | 9 |
| DRUG INTERACTION | 8 |
| DRUG-INDUCED LIVER INJURY | 8 |
| RENAL FAILURE | 8 |
| ACUTE HEPATIC FAILURE | 5 |
| DRUG ABUSE | 5 |
| HEPATIC FAILURE | 5 |
| HYPOTENSION | 5 |
| MULTI-ORGAN FAILURE | 5 |
| ALCOHOL INTOLERANCE | 4 |
| CONFUSIONAL STATE | 4 |
| CONVULSION | 4 |
| DYSPNOEA | 4 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (504, 46.8% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DRUG INTERACTION | 82 |
| TOXICITY TO VARIOUS AGENTS | 37 |
| OVERDOSE | 35 |
| CONFUSIONAL STATE | 32 |
| ACUTE KIDNEY INJURY | 29 |
| TOXIC ENCEPHALOPATHY | 29 |
| NAUSEA | 27 |
| MILK-ALKALI SYNDROME | 26 |
| SOMNOLENCE | 26 |
| DRUG ABUSE | 25 |
| FATIGUE | 25 |
| HYPERCALCAEMIA | 25 |
| VOMITING | 25 |
| CONDITION AGGRAVATED | 24 |
| MALAISE | 24 |
| ASTHENIA | 23 |
| PSYCHOTIC DISORDER | 20 |
| ENCEPHALOPATHY | 19 |
| SUICIDE ATTEMPT | 19 |
How to read disulfiram FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 1,076 voluntary reports linked to disulfiram (Antabuse), 2004-2025. Death is listed on 111 (10.3%). Hospitalization appears on 504 (46.8%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with disulfiram
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 1,037 FAERS cases (Δ 39 lighter vs disulfiram); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,132 FAERS cases (Δ 56 heavier vs disulfiram); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,152 FAERS cases (Δ 76 heavier vs disulfiram); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 1,191 FAERS cases (Δ 115 heavier vs disulfiram); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.8 pp vs disulfiram's DEATH-HEAVY): CASELOAD · HOSP-MID.
disulfiram stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.