LOW-VOLUME · SEIZURE
cenobamate Side Effects
cenobamate (also sold as Xcopri) is a LOW-VOLUME FAERS extract #370 of 524 by FAERS report count. Still opens on SEIZURE: SEIZURE leads at 1,815 reports (28.1% of the book).
Data updated 2026-05-15
- 6,460
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
Among 6,460 FAERS reports for cenobamate, SEIZURE is the most-reported reaction (1,815). Volume band LOW-VOLUME #370 of 524 by FAERS report count.
Thinner FAERS extract for cenobamate (Xcopri) (6,460 reports #370 of 524 by FAERS report count). SEIZURE leads at 1,815 reports (28.1% of the book). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2019–2025). Stamps WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
SEIZURE leads 1,815 of 6,460 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (486 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 156 reports (2.4% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| DEATH | 64 |
| SEIZURE | 27 |
| CARDIAC ARREST | 13 |
| SUDDEN UNEXPLAINED DEATH IN EPILEPSY | 12 |
| COMPLETED SUICIDE | 11 |
| CARDIO-RESPIRATORY ARREST | 9 |
| FALL | 5 |
| AGITATION | 4 |
| HOSPITALISATION | 4 |
| HYPOTENSION | 4 |
| SOMNOLENCE | 4 |
| TOXICITY TO VARIOUS AGENTS | 4 |
| BRADYCARDIA | 3 |
| CHEST PAIN | 3 |
| DECREASED APPETITE | 3 |
| DIZZINESS | 3 |
| HEAD INJURY | 3 |
Reactions in Hospitalization Reports
Hospitalization mid-share (1,300, 20.1%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| SEIZURE | 486 |
| HOSPITALISATION | 159 |
| FALL | 158 |
| SOMNOLENCE | 127 |
| DIZZINESS | 121 |
| DRUG INTERACTION | 107 |
| FATIGUE | 105 |
| BALANCE DISORDER | 58 |
| GAIT DISTURBANCE | 58 |
| VOMITING | 57 |
| ASTHENIA | 50 |
| PNEUMONIA | 47 |
| DECREASED APPETITE | 46 |
| STATUS EPILEPTICUS | 45 |
| DYSARTHRIA | 44 |
How to read cenobamate FAERS figures (WATCHLIST · DEATH-MARKED · HOSP-MID)
FAERS holds 6,460 voluntary reports linked to cenobamate (Xcopri), 2019-2025. Death is listed on 156 (2.4%). Hospitalization appears on 1,300 (20.1%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with cenobamate
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 6,450 FAERS cases (Δ 10 lighter vs cenobamate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 6,445 FAERS cases (Δ 15 lighter vs cenobamate); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 6,501 FAERS cases (Δ 41 heavier vs cenobamate); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 6,539 FAERS cases (Δ 79 heavier vs cenobamate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 59.7 pp vs cenobamate's DEATH-MARKED): CASELOAD · HOSP-MID.
cenobamate stamps WATCHLIST · SEX-BALANCED; class peers and methodology beat restating the same FAERS caveats on every effects URL.