MID-VOLUME · FEMALE-LED
risedronate Side Effects
risedronate (also sold as Actonel) sits MID-VOLUME #189 of 524 by FAERS report count. Lead signal: FEMALE-LED - 86% of sex-coded reports are female (23,730 F / 3,957 M). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 30,089
- FAERS reports
FDA Adverse Event Reporting System extract for risedronate. Stamp set CASELOAD · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
risedronate reporting skew - 86% of sex-coded reports are female (23,730 F / 3,957 M). Volume band MID-VOLUME #189 of 524 by FAERS report count; caseload CASELOAD.
Mid-book FAERS page for risedronate (Actonel) (30,089 reports). Signature FEMALE-LED. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (2003–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.
ARTHRALGIA leads 3,730 of 30,089 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (86% of sex-coded rows)
Age peak 45-64 (6,555 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (2,696 reports, 9.0%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 572 |
| PAIN | 547 |
| VOMITING | 544 |
| DIARRHOEA | 543 |
| FATIGUE | 515 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 511 |
| ARTHRALGIA | 505 |
| CONFUSIONAL STATE | 505 |
| JOINT SWELLING | 500 |
| ASTHENIA | 497 |
| RHEUMATOID ARTHRITIS | 496 |
| DYSPNOEA | 485 |
| SYSTEMIC LUPUS ERYTHEMATOSUS | 484 |
| WHEEZING | 484 |
| INFUSION RELATED REACTION | 474 |
| LOWER RESPIRATORY TRACT INFECTION | 474 |
| PSORIATIC ARTHROPATHY | 474 |
| RASH | 474 |
| SWELLING | 474 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (12,023, 40.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| PAIN | 1,849 |
| ARTHRALGIA | 1,775 |
| FATIGUE | 1,643 |
| DIARRHOEA | 1,641 |
| NAUSEA | 1,627 |
| FALL | 1,406 |
| VOMITING | 1,356 |
| DYSPNOEA | 1,315 |
| RHEUMATOID ARTHRITIS | 1,299 |
| HYPERTENSION | 1,287 |
| ASTHENIA | 1,277 |
| PNEUMONIA | 1,260 |
| HEADACHE | 1,256 |
| MALAISE | 1,221 |
| DRUG HYPERSENSITIVITY | 1,216 |
| PYREXIA | 1,177 |
| JOINT SWELLING | 1,157 |
| CONDITION AGGRAVATED | 1,142 |
How to read risedronate FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 30,089 voluntary reports linked to risedronate (Actonel), 2003-2025. Death is listed on 2,696 (9.0%). Hospitalization appears on 12,023 (40.0%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 86% of sex-coded reports are female (23,730 F / 3,957 M).
Read with risedronate
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 29,879 FAERS cases (Δ 210 lighter vs risedronate); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 29,874 FAERS cases (Δ 215 lighter vs risedronate); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 29,813 FAERS cases (Δ 276 lighter vs risedronate); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 30,400 FAERS cases (Δ 311 heavier vs risedronate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.1 pp vs risedronate's DEATH-HEAVY): CASELOAD · HOSP-MID.
risedronate stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.