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Two medicines, side by side

Sennosides vs magnesium citrate

Sennosides and magnesium citrate are both labeled for constipation. Pharmacies paid $0.0258 per senna 8.6 mg tablet and $0.0066 per mL (Magnesium citrate solution) (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.

Check it at the source: the sennosides FDA label on DailyMed (effective May 30, 2024); the magnesium citrate FDA label on DailyMed (effective September 1, 2026).

Highlights of the sennosides record

Sennosides · label of May 30, 2024

Used for

From the label: indications

Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.0258 per tablet

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the magnesium citrate record

Magnesium citrate · label of September 1, 2026

Used for

From the label: indications

relieves occasional constipation (irregularity) generally produces bowel movement in 1/2 to 6 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.0066 per mL

Supply and safety

Shortage
No current entry
Recalls
1

Source: FDA drug labels via openFDA (Sennosides label of May 30, 2024, Magnesium citrate label of September 1, 2026); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do sennosides and magnesium citrate differ on the record?

SennosidesMagnesium citrate
Labeled forConstipationConstipation
Pharmacologic classn/an/a
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)n/an/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.0258 per tablet (Senna 8.6 mg tablet)$0.0066 per mL (Magnesium citrate solution)
12-month price change+4%+6%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded01
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)41,5946,104
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to sennosides
every medicine labeled for the same conditions