Two medicines, side by side
Sennosides vs docusate
Sennosides and docusate are both labeled for constipation. Pharmacies paid $0.0258 per senna 8.6 mg tablet and $0.0276 per unit (Docusate sodium 100 mg softgel) (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.
Check it at the source: the sennosides FDA label on DailyMed (effective May 30, 2024); the docusate FDA label on DailyMed (effective February 6, 2025).
Highlights of the sennosides record
Sennosides · label of May 30, 2024
Used for
From the label: indicationsRelieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours
On the market
- Earliest approval on file
- n/a
- Generic labelers
- none listed
- Pharmacy cost
- $0.0258 per tablet
Supply and safety
- Shortage
- No current entry
- Recalls
- 0
Highlights of the docusate record
Docusate · label of February 6, 2025
Used for
From the label: indicationsrelieves occasional constipation (irregularity) generally produces bowel movement in 12 to 72 hours
On the market
- Earliest approval on file
- n/a
- Generic labelers
- none listed
- Pharmacy cost
- $0.0276 per unit
Supply and safety
- Shortage
- No current entry
- Recalls
- 2
Source: FDA drug labels via openFDA (Sennosides label of May 30, 2024, Docusate label of February 6, 2025); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)
How do sennosides and docusate differ on the record?
| Sennosides | Docusate | |
|---|---|---|
| Labeled for | Constipation | Constipation |
| Pharmacologic class | n/a | n/a |
| How it works (label) | n/a | n/a |
| Half-life (label) | n/a | n/a |
| Earliest approval on file (Drugs@FDA) | n/a | n/a |
| First generic approved | none | none |
| Generic labelers (NDC) | none listed | none listed |
| Pharmacy cost (NADAC, each one's most listed form; strengths differ) | $0.0258 per tablet (Senna 8.6 mg tablet) | $0.0276 per unit (Docusate sodium 100 mg softgel) |
| 12-month price change | +4% | -5% |
| Boxed warning | No | No |
| Shortage now | No current entry | No current entry |
| Recalls recorded | 0 | 2 |
| FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used) | 41,594 | 58,569 |
| DEA schedule | none | none |
Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)
What next?
- Alternatives to sennosides
- every medicine labeled for the same conditions