Two medicines, side by side
Micafungin vs voriconazole
Micafungin and voriconazole are both labeled for fungal infections. Drugs@FDA records approvals of micafungin since 2005 and of voriconazole since 2002. In FDA's classes, micafungin is an echinocandin antifungal and voriconazole an azole antifungal.
Check it at the source: the micafungin FDA label on DailyMed (effective November 8, 2025); the voriconazole FDA label on DailyMed (effective February 26, 2026).
Highlights of the micafungin record
Micafungin (Mycamine) · label of November 8, 2025
Used for
From the label: indicationsMicafungin for injection is indicated for: Treatment of Candidemia, Acute Disseminated Candidiasis, Candida Peritonitis and Abscesses in adult and pediatric patients 4 months of age and older [see Clinical Studies ( 14.1 ) and Use in Specific Populations ( 8.4 )]. […]
On the market
- Earliest approval on file
- March 16, 2005
- Generic labelers
- 10 labelers
- Pharmacy cost
- Not in the survey
Supply and safety
- Shortage
- A presentation being discontinued
- Recalls
- 4
Highlights of the voriconazole record
Voriconazole (Vfend) · label of February 26, 2026
Used for
From the label: indicationsVFEND is an azole antifungal indicated for the treatment of adults and pediatric patients 2 years of age and older with: • Invasive aspergillosis ( 1.1 ) • Candidemia in non-neutropenics and other deep tissue Candida infections ( 1.2 ) • Esophageal candidiasis ( 1.3 ) • Serious fungal infections caused by Scedosporium apiospermum and Fusarium species including Fusarium solani, in patients intolerant of, or […]
On the market
- Earliest approval on file
- May 24, 2002
- Generic labelers
- 31 labelers
- Pharmacy cost
- $1.88 per tablet
Supply and safety
- Shortage
- A presentation being discontinued
- Recalls
- 4
Source: FDA drug labels via openFDA (Micafungin label of November 8, 2025, Voriconazole label of February 26, 2026); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)
How do micafungin and voriconazole differ on the record?
In FDA's classes, micafungin is an echinocandin antifungal and voriconazole an azole antifungal.
How each works, in its label's words: Micafungin, “Micafungin is a member of the echinocandin class of antifungal agents [see Microbiology ( 12.4 )].”; Voriconazole, “Voriconazole is an antifungal drug [see Microbiology (12.4) ].”
Generics: micafungin since 2019; voriconazole since 2010 (Drugs@FDA).
| Micafungin | Voriconazole | |
|---|---|---|
| Labeled for | Fungal infections | Fungal infections |
| Pharmacologic class | Echinocandin Antifungal | Azole Antifungal |
| How it works (label) | Micafungin is a member of the echinocandin class of antifungal agents [see Microbiology ( 12.4 )]. | Voriconazole is an antifungal drug [see Microbiology (12.4) ]. |
| Half-life (label) | n/a | n/a |
| Earliest approval on file (Drugs@FDA) | March 16, 2005 | May 24, 2002 |
| First generic approved | May 17, 2019 | April 22, 2010 |
| Generic labelers (NDC) | 10 labelers | 31 labelers |
| Pharmacy cost (NADAC, each one's most listed form; strengths differ) | n/a | $1.88 per tablet (Voriconazole 200 mg tablet) |
| 12-month price change | n/a | -2% |
| Boxed warning | No | No |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
| Recalls recorded | 4 | 4 |
| FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used) | 6,383 | 30,201 |
| DEA schedule | none | none |
Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)
Do their labels mention each other?
Micafungin label, drug interactionsDrugs on Micafungin CYP3A4, CYP2C9 and CYP2C19 Inhibitors Co-administration of micafungin with cyclosporine, itraconazole, voriconazole and fluconazole did not alter the pharmacokinetics of micafungin.
Micafungin label, drug interactionsDrugs on Micafungin in Sodium Chloride Injection CYP3A4, CYP2C9 and CYP2C19 Inhibitors Co-administration of Micafungin in Sodium Chloride Injection with cyclosporine, itraconazole, voriconazole and fluconazole did not alter the pharmacokinetics of micafungin.
Source: FDA drug labels via openFDA
What next?
- Alternatives to micafungin
- every medicine labeled for the same conditions