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Two medicines, side by side

Magnesium hydroxide vs sennosides

Magnesium hydroxide and sennosides are both labeled for constipation. Pharmacies paid $0.0095 per mL (Milk of magnesia suspension) and $0.0258 per senna 8.6 mg tablet (NADAC, October 7, 2026); the strengths differ, so the two prices are not like for like.

Check it at the source: the magnesium hydroxide FDA label on DailyMed (effective August 21, 2026); the sennosides FDA label on DailyMed (effective May 30, 2024).

Highlights of the magnesium hydroxide record

Magnesium hydroxide · label of August 21, 2026

Used for

From the label: indications

relieves occasional constipation (irregularity). This product usually produces bowel movement in 1/2 to 6 hours.

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.0095 per mL

Supply and safety

Shortage
No current entry
Recalls
6

Highlights of the sennosides record

Sennosides · label of May 30, 2024

Used for

From the label: indications

Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.0258 per tablet

Supply and safety

Shortage
No current entry
Recalls
0

Source: FDA drug labels via openFDA (Magnesium hydroxide label of August 21, 2026, Sennosides label of May 30, 2024); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do magnesium hydroxide and sennosides differ on the record?

Magnesium hydroxideSennosides
Labeled forConstipation, Acid reflux and ulcersConstipation
Pharmacologic classn/an/a
How it works (label)n/an/a
Half-life (label)n/an/a
Earliest approval on file (Drugs@FDA)n/an/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$0.0095 per mL (Milk of magnesia suspension)$0.0258 per tablet (Senna 8.6 mg tablet)
12-month price change-2%+4%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded60
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)13,45841,594
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to magnesium hydroxide
every medicine labeled for the same conditions