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latanoprost vs travoprost

Side-by-side comparison of latanoprost and travoprost Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
latanoprost Prostaglandin Analog (Ophthalmic)
travoprost Prostaglandin Analog (Ophthalmic)
Type
latanoprost Prescription
travoprost Prescription
Summary
latanoprost

Latanoprost eye drops help lower pressure inside your eye. It is used if you have open-angle glaucoma or ocular hypertension.

travoprost

Travoprost eye drops help lower pressure in the eye. It is used to treat glaucoma and high eye pressure.

What It Treats
latanoprost

Latanoprost eye drops are used to lower high pressure in your eyes. This medicine is for people who have open-angle glaucoma or ocular hypertension. These conditions can damage your optic nerve and cause vision loss.

travoprost

Travoprost eye drops are used to lower high pressure inside your eye. This medicine can treat open-angle glaucoma, a condition where the optic nerve is damaged. It also treats ocular hypertension, which is higher than normal pressure in the eye.

How It Works
latanoprost

Latanoprost is like a natural substance in your body. It works by helping fluid drain better from inside your eye. This lowers the pressure in your eye.

travoprost

Travoprost is like a natural substance in your body. It works by helping fluid drain better from inside your eye. This lowers the pressure in your eye.

Common Side Effects
latanoprost
  • Blurred vision
  • Burning or stinging
  • Redness of the eye
  • Feeling like something is in your eye
  • Itching
travoprost
  • Redness of the eye (30-50% of users)
FAERS Reports
latanoprost
  • The medicine is not working 5,915
  • The medicine is not effective 3,134
  • Tiredness 2,228
  • Eye feels sore or scratchy 2,190
  • Pressure inside the eye increased 1,769
travoprost
  • Treatment not working 1,945
  • Medicine not effective 528
  • Eye redness 490
  • Eye irritation 478
  • Eye pain 336
Serious Warnings
latanoprost

Latanoprost can cause your iris (the colored part of your eye), eyelid, and eyelashes to get darker. The iris color change may be permanent. Eyelash changes, like increased length and thickness, are usually reversible when you stop using the medicine. Use with caution if you have a history of eye inflammation or herpes keratitis.

travoprost

Travoprost can cause your iris (the colored part of your eye), eyelid, and eyelashes to darken. The iris change may be permanent. Eyelash changes, like increased length and thickness, are usually reversible when you stop using the drops. Use caution if you have inflammation inside your eye, as this medicine may worsen it.

Pregnancy
latanoprost

It is not known if latanoprost is safe to use during pregnancy. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

travoprost

It is not known if travoprost is safe to use during pregnancy. Animal studies suggest a risk to the fetus. Talk to your doctor if you are pregnant or plan to become pregnant.

Also Compare — Nearby Drugs

How to Read This latanoprost vs travoprost Comparison

latanoprost is classified in the Prostaglandin Analog (Ophthalmic) drug class, while travoprost sits within the Prostaglandin Analog (Ophthalmic) class. Because both drugs share the same classification, they are often considered interchangeable in theory — but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, latanoprost has 15,236 submissions while travoprost has 3,777. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between latanoprost and travoprost — always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.