itraconazole vs valbenazine
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Side-by-side comparison of itraconazole and valbenazine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Valbenazine Concomitant drug dose reduction is necessary. Refer to the valbenazine prescribing information for dosing instructions.
Sporanox
Ingrezza
Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.
Ingrezza and Ingrezza Sprinkle are medicines used to treat movement problems. They can help with tardive dyskinesia and chorea caused by Huntington's disease.
Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.
This medicine treats tardive dyskinesia in adults. Tardive dyskinesia causes repetitive, uncontrolled movements. It also treats chorea, which is involuntary, jerky movements, in adults with Huntington's disease.
Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.
Ingrezza works by affecting a protein in your brain called VMAT2. This protein helps control the release of certain chemicals. By blocking VMAT2, Ingrezza helps reduce unwanted movements.
- • Nausea
- • Rash
- • Headache
- • Sleepiness
- • Lethargy
- • Sedation
- • Urticaria (hives)
- • Rash
- Drug Interaction 1,118
- Pyrexia 568
- Dyspnoea 474
- Pneumonia 461
- Nausea 445
- Somnolence 2,412
- Fatigue 1,646
- Tremor 1,539
- Tardive Dyskinesia 1,471
- Fall 1,104
Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.
Ingrezza can increase the risk of depression and suicidal thoughts in people with Huntington's disease. Your doctor will monitor you closely for any changes in mood or behavior. Tell your doctor right away if you have any thoughts of harming yourself.
You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.
Ingrezza may harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while taking Ingrezza.
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How to Read This itraconazole vs valbenazine Comparison
itraconazole is classified in the Azole Antifungal drug class, while valbenazine sits within the VMAT2 Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, itraconazole has 3,066 submissions while valbenazine has 8,172. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to itraconazole prevents your body from processing valbenazine normally. this causes the drug to reach higher levels in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for itraconazole or valbenazine.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.