itraconazole vs triazolam
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Side-by-side comparison of itraconazole and triazolam. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
major Known Drug Interaction
Lurasidone Midazolam (oral) a Pimozide Triazolam a Contraindicated during and 2 weeks after itraconazole treatment.
Sporanox
Halcion
Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.
Triazolam (Halcion) is a medication used for the short-term treatment of insomnia. It belongs to a class of drugs called benzodiazepines, which help you fall asleep.
Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.
Triazolam is used to treat insomnia in adults. Insomnia is when you have trouble falling asleep or staying asleep. This medicine is only for short-term use, usually for 7 to 10 days.
Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.
Triazolam works by slowing down activity in the brain. This helps you to relax and fall asleep. It affects certain chemicals in your brain called neurotransmitters.
- • Nausea
- • Rash
- • Headache
- • Drowsiness
- • Headache
- • Dizziness
- • Nervousness
- • Light-headedness
- Drug Interaction 1,118
- Pyrexia 568
- Dyspnoea 474
- Pneumonia 461
- Nausea 445
- Drug Abuse 519
- Sopor 402
- Nausea 352
- Overdose 350
- Fall 315
Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.
Taking triazolam with opioid pain medicines can cause very serious problems, including slowed or stopped breathing, coma, and death. Because of these risks, doctors will only prescribe opioid pain medicines with triazolam when other treatment options are not sufficient. Do not misuse this medicine. Misuse can lead to addiction, overdose, or death. Stopping triazolam suddenly can cause dangerous withdrawal symptoms. Talk to your doctor before stopping this medicine.
You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.
Taking triazolam late in pregnancy may cause sedation or withdrawal symptoms in the newborn. If you are pregnant or plan to become pregnant, talk to your doctor about the risks and benefits of taking triazolam. A registry exists to track outcomes in women who take psychiatric medications, including triazolam, during pregnancy.
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How to Read This itraconazole vs triazolam Comparison
itraconazole is classified in the Azole Antifungal drug class, while triazolam sits within the Benzodiazepine (Hypnotic) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, itraconazole has 3,066 submissions while triazolam has 1,938. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known major interaction flagged in FDA labeling, attributed to itraconazole prevents your body from clearing triazolam, which can make the sleep medicine much more powerful and potentially dangerous.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for itraconazole or triazolam.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.