itraconazole vs oxycodone

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Side-by-side comparison of itraconazole and oxycodone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Alfentanil Buprenorphine (IV and sublingual) Oxycodone a Sufentanil Monitor for adverse reactions.

Drug Class
itraconazole Azole Antifungal
oxycodone Opioid Analgesic
Type
itraconazole Prescription
oxycodone Prescription
Summary
itraconazole

Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.

oxycodone

Oxycodone is a strong pain medicine. It is used to treat severe pain that is not helped by other treatments.

What It Treats
itraconazole

Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.

oxycodone

Oxycodone is used to manage severe pain. It is for pain that requires an opioid medicine. You should only use it when other pain treatments are not enough. Talk to your doctor about other options if possible.

How It Works
itraconazole

Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.

oxycodone

Oxycodone works by changing how your brain and nervous system respond to pain. It attaches to certain receptors in the brain. This helps to block pain signals and reduce pain.

Common Side Effects
itraconazole
  • Nausea
  • Rash
  • Headache
oxycodone
  • Feeling sick to your stomach
  • Constipation
  • Throwing up
  • Headache
  • Itching
FAERS Reports
itraconazole
  • Drug Interaction 1,118
  • Pyrexia 568
  • Dyspnoea 474
  • Pneumonia 461
  • Nausea 445
oxycodone
  • Drug Dependence 27,480
  • Pain 26,409
  • Death 19,598
  • Overdose 19,081
  • Toxicity To Various Agents 16,253
Serious Warnings
itraconazole

Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.

oxycodone

Oxycodone can cause serious, life-threatening risks: * Addiction, abuse, and misuse can lead to overdose and death. Your doctor will check your risk before prescribing and during treatment. * It can cause very slow or stopped breathing, especially when you start taking it or after a dose increase. * If a child accidentally takes even one dose, it can cause a fatal overdose. * Taking it with benzodiazepines (like Xanax) or other depressants (like alcohol) can cause sleepiness, slowed breathing, coma, and death. * Using oxycodone for a long time during pregnancy can cause withdrawal symptoms in the newborn. * Taking oxycodone with certain other medicines can cause dangerous side effects.

Pregnancy
itraconazole

You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.

oxycodone

Using oxycodone for a long time during pregnancy can cause withdrawal symptoms in the baby after birth. Talk to your doctor about the risks if you are pregnant or plan to become pregnant. Oxycodone is not recommended during labor, as it can cause breathing problems in the newborn.

Also Compare, Nearby Drugs

How to Read This itraconazole vs oxycodone Comparison

itraconazole is classified in the Azole Antifungal drug class, while oxycodone sits within the Opioid Analgesic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, itraconazole has 3,066 submissions while oxycodone has 108,821. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to itraconazole stops your body from processing the pain medicine oxycodone, which can lead to higher levels of the drug in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for itraconazole or oxycodone.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.