insulin human/insulin isophane vs olanzapine
Side-by-side comparison of insulin human/insulin isophane and olanzapine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Drugs that May Decrease the Blood Glucose Lowering Effect of HUMULIN 70/30 Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones.
Recommendation: Your doctor may need to adjust your insulin dose or monitor your blood sugar more closely.
Humulin 70/30
Zyprexa
Humulin 70/30 is a mix of two types of insulin. It helps control blood sugar in adults with diabetes.
Olanzapine is a medicine used to treat certain mental disorders. It helps to balance chemicals in the brain to improve mood and behavior.
Humulin 70/30 is used to improve blood sugar control in adults with diabetes. Diabetes is a condition where your body does not make enough insulin or cannot use insulin properly. This medicine helps your body use sugar from the food you eat for energy.
Olanzapine is used to treat schizophrenia in adults and teens (13-17). It also treats manic or mixed episodes of bipolar I disorder in adults and teens (13-17). In adults, it can be used with other medicines to treat bipolar depression.
This medicine is a mix of two insulins: one that works quickly and one that works longer. The short-acting insulin helps control blood sugar after meals. The intermediate-acting insulin works between meals and during the night.
Olanzapine is an atypical antipsychotic. It works by affecting the levels of certain chemicals in your brain. These chemicals include dopamine and serotonin, which can help improve mood, thinking, and behavior.
- • Low blood sugar (hypoglycemia)
- • Allergic reactions like redness and swelling at the injection site
- • Skin changes at the injection site
- • Weight gain
- • Dizziness
- • Weight gain
- • Increased appetite
- • Dry mouth
- • Constipation
- High blood sugar 10,557
- Low blood sugar 3,451
- Wrong dose given 2,164
- Low blood sugar 1,532
- Feeling sick to your stomach 1,473
- Weight gain 6,721
- Diabetes 5,388
- The medicine is interacting with another medicine 4,050
- Poisoning from different substances 3,965
- Sleepiness 3,838
Never share a Humulin 70/30 KwikPen or syringe with anyone else, even if the needle is changed. Sharing pens or syringes can spread blood-borne diseases. Changes in your insulin dose should be done carefully with your doctor's supervision. Low blood sugar can be life-threatening. Fluid retention and heart failure can occur if you also take thiazolidinediones (TZDs).
Olanzapine can increase the risk of death in older adults with dementia-related psychosis. Olanzapine is not approved to treat this condition. When using olanzapine with fluoxetine, read the Symbyax label for more warnings.
Tell your doctor if you are pregnant or plan to become pregnant. Good control of diabetes is important during pregnancy. This medicine may pass into breast milk, but it is not expected to harm your baby.
If you take olanzapine during the third trimester of pregnancy, your baby may have withdrawal symptoms after birth. There is a pregnancy registry to monitor outcomes in women who take atypical antipsychotics during pregnancy. Talk to your doctor.
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How to Read This insulin human/insulin isophane vs olanzapine Comparison
insulin human/insulin isophane is classified in the Intermediate-Acting Insulin Combination drug class, while olanzapine sits within the Atypical Antipsychotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, insulin human/insulin isophane has 19,177 submissions while olanzapine has 23,962. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to olanzapine can make insulin less powerful, which may lead to higher blood sugar levels than usual.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between insulin human/insulin isophane and olanzapine - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.