fesoterodine vs verapamil
According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.
Side-by-side comparison of fesoterodine and verapamil. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
No dosing adjustments are recommended in the presence of moderate CYP3A4 inhibitors (e.g., erythromycin, fluconazole, diltiazem, verapamil and grapefruit juice).
Toviaz
Calan, Verelan
Fesoterodine is a medicine that helps control an overactive bladder. It reduces the feeling of needing to go to the bathroom so often.
Verapamil is a drug that helps to lower blood pressure and treat chest pain (angina) and irregular heartbeats (arrhythmias). It works by relaxing blood vessels and slowing down the heart rate.
This medicine treats overactive bladder (OAB) in adults. OAB can cause you to feel a sudden need to urinate. It can also cause you to urinate more often than normal, and leak urine.
Verapamil is used to treat chest pain called angina. This includes angina that happens when you are resting or during normal activity. It is also used to control your heart rate if you have a fast or irregular heartbeat, such as atrial fibrillation or atrial flutter. Verapamil also treats high blood pressure.
Fesoterodine belongs to a class of drugs called anticholinergics. It works by blocking certain nerve signals to the bladder. This helps to relax the bladder muscles and reduce the urge to urinate.
Verapamil belongs to a class of drugs called calcium channel blockers. It works by blocking calcium from entering heart and blood vessel cells. This relaxes and widens blood vessels, which lowers blood pressure and makes it easier for the heart to pump.
- • Dry mouth
- • Constipation
- • Constipation
- • Shortness of breath
- • Dizziness
- • Slow heart rate (less than 50 beats per minute)
- • Nausea
- Dry mouth 823
- Fall 529
- Tiredness 505
- Constipation 503
- Unable to empty bladder 502
- Dyspnoea 356
- Nausea 341
- Drug Interaction 316
- Dizziness 286
- Hypotension 280
Fesoterodine can cause swelling of the face, lips, tongue, or throat. This can be life-threatening, so stop taking the medicine and get medical help right away if this happens. Fesoterodine is not recommended if you have a blockage in your bladder or have problems with food moving through your digestive system. Use with caution if you have narrow-angle glaucoma or myasthenia gravis.
You should not take this medicine if you have severe heart problems, very low blood pressure, or certain types of irregular heartbeats without a pacemaker. Talk to your doctor if you have any of these conditions.
It is not known if fesoterodine can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if fesoterodine passes into breast milk. Talk to your doctor about the best way to feed your baby if you are taking this medicine.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if verapamil will harm your unborn baby. Verapamil can pass into breast milk, so talk to your doctor about the best way to feed your baby if you take this medicine.
Also Compare, Nearby Drugs
Compare fesoterodine with
Compare verapamil with
How to Read This fesoterodine vs verapamil Comparison
fesoterodine is classified in the Anticholinergic (Overactive Bladder) drug class, while verapamil sits within the Calcium Channel Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fesoterodine has 2,862 submissions while verapamil has 1,579. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to verapamil blocks the enzyme responsible for breaking down fesoterodine, which may slightly raise the level of the drug in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for fesoterodine or verapamil.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.