enalapril vs vasopressin

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Side-by-side comparison of enalapril and vasopressin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

7.4 Drugs Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasopressin injection.

Drug Class
enalapril ACE Inhibitor
vasopressin Vasopressin Receptor Agonist
Type
enalapril Prescription
vasopressin Prescription
Summary
enalapril

Enalapril (Vasotec) is a medicine that lowers blood pressure and helps treat heart failure. It belongs to a class of drugs called ACE inhibitors.

vasopressin

Vasopressin injection helps raise blood pressure in adults with shock. It is used when fluids and other medicines don't work well enough.

What It Treats
enalapril

Enalapril is used to treat high blood pressure. It can be used alone or with other blood pressure medicines, like water pills. Enalapril also treats symptomatic congestive heart failure, usually with other medicines. It can also help clinically stable patients with left ventricular dysfunction.

vasopressin

Vasopressin injection is used to increase blood pressure. It is for adults who have vasodilatory shock. This is when blood vessels relax too much, causing low blood pressure. It is used when fluids and other medicines called catecholamines are not enough to raise blood pressure.

How It Works
enalapril

Enalapril blocks a substance in your body that tightens blood vessels. This helps your blood vessels relax and widens them. As a result, blood pressure is lowered, and blood can flow more easily.

vasopressin

Vasopressin is a hormone that makes blood vessels get tighter. This helps to increase blood pressure. It can also affect how your kidneys handle water.

Common Side Effects
enalapril
  • Headache
  • Dizziness
  • Fatigue
  • Cough
vasopressin
  • Decreased heart output
  • Slow heart rate
  • Fast or irregular heart rate
  • Low sodium levels in the blood
  • Reduced blood flow to the heart
FAERS Reports
enalapril
  • Diarrhoea 2,807
  • Dyspnoea 2,659
  • Nausea 2,574
  • Fatigue 2,377
  • Drug Interaction 2,336
vasopressin
  • Hypotension 486
  • Cardiogenic Shock 389
  • Sepsis 380
  • Multiple Organ Dysfunction Syndrome 375
  • Condition Aggravated 359
Serious Warnings
enalapril

This drug can harm your unborn baby. Stop taking enalapril as soon as you know you are pregnant.

vasopressin

Vasopressin can worsen heart function. It can also cause a type of diabetes where you pee a lot. Your doctor will check your electrolytes and urine after you stop taking it.

Pregnancy
enalapril

Do not take enalapril if you are pregnant because it can cause harm or death to the developing fetus. Talk to your doctor about safe alternatives if you are breastfeeding.

vasopressin

Vasopressin may cause the uterus to contract, which could be a problem during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if vasopressin passes into breast milk.

Also Compare, Nearby Drugs

How to Read This enalapril vs vasopressin Comparison

enalapril is classified in the ACE Inhibitor drug class, while vasopressin sits within the Vasopressin Receptor Agonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, enalapril has 12,753 submissions while vasopressin has 1,989. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to enalapril can cause the body to hold onto more water, which adds to the effects of vasopressin. this can lead to higher blood pressure and more water retention.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for enalapril or vasopressin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.