diltiazem vs suvorexant
According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.
Side-by-side comparison of diltiazem and suvorexant. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The recommended dose of BELSOMRA is 5 mg in subjects receiving moderate CYP3A inhibitors (e.g., amprenavir, aprepitant, atazanavir, ciprofloxacin, diltiazem, erythromycin, fluconazole, fosamprenavir, grapefruit juice, imatinib, verapamil).
Cardizem, Tiazac
Belsomra
Diltiazem is a medicine that helps lower high blood pressure and prevent chest pain. It belongs to a class of drugs called calcium channel blockers.
Belsomra is a prescription medicine used to treat insomnia. It helps you fall asleep and stay asleep.
Diltiazem is used to treat high blood pressure. It can be used alone or with other blood pressure medicines. Diltiazem also helps manage chronic stable angina (chest pain) and angina caused by spasms in the heart's blood vessels.
Belsomra is used to treat insomnia in adults. Insomnia means you have trouble falling asleep, staying asleep, or both. This medicine can help you sleep better.
Diltiazem works by relaxing blood vessels, which lowers blood pressure. It also reduces the heart's workload, which can prevent chest pain. This medicine blocks calcium from entering heart and blood vessel cells.
Belsomra works by blocking orexin, a chemical in your brain that keeps you awake. By blocking orexin, Belsomra helps to reduce wakefulness and allows you to fall asleep.
- • Swelling in your ankles or feet
- • Headache
- • Dizziness
- • Slow heart rate
- • Constipation
- • Sleepiness
- Dyspnoea 3,202
- Fatigue 2,638
- Nausea 2,372
- Pain 2,365
- Dizziness 2,091
- Nightmare 736
- Somnolence 726
- Insomnia 674
- Abnormal Dreams 599
- Headache 535
Diltiazem can interact with other heart medications. Tell your doctor if you take beta-blockers or digoxin. Using diltiazem with these drugs can cause heart problems. Your doctor may need to adjust your dosages.
Belsomra can cause you to feel sleepy during the day and can impair your ability to drive. Do not drive or do other activities that require you to be fully alert, especially if you take the 20 mg dose. Belsomra may also worsen depression or cause suicidal thoughts. Tell your doctor right away if you have any new or worsening mood changes. Complex sleep behaviors like sleepwalking have also been reported. Stop taking Belsomra and tell your doctor if this happens.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if diltiazem will harm your unborn baby. Diltiazem passes into breast milk, so talk to your doctor about breastfeeding while taking this medicine.
It is not known if Belsomra can harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if Belsomra passes into breast milk. Talk to your doctor about the best way to feed your baby if you take Belsomra.
Also Compare, Nearby Drugs
Compare diltiazem with
Compare suvorexant with
How to Read This diltiazem vs suvorexant Comparison
diltiazem is classified in the Calcium Channel Blocker drug class, while suvorexant sits within the Orexin Receptor Antagonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, diltiazem has 12,668 submissions while suvorexant has 3,270. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to diltiazem blocks the enzyme that breaks down suvorexant, which can cause the sleep medicine to build up in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for diltiazem or suvorexant.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.