diltiazem vs dutasteride/tamsulosin
Side-by-side comparison of diltiazem and dutasteride/tamsulosin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.6 Calcium Channel Antagonists Dutasteride Coadministration of verapamil or diltiazem decreases dutasteride clearance and leads to increased exposure to dutasteride.
Recommendation: Your doctor may need to monitor you more closely for side effects or adjust your medication dose.
Cardizem, Tiazac
Jalyn
Diltiazem is a medicine that helps lower high blood pressure and prevent chest pain. It belongs to a class of drugs called calcium channel blockers.
This medicine combines two drugs to treat enlarged prostate in men. It helps improve urine flow and reduce symptoms.
Diltiazem is used to treat high blood pressure. It can be used alone or with other blood pressure medicines. Diltiazem also helps manage chronic stable angina (chest pain) and angina caused by spasms in the heart's blood vessels.
This medicine treats benign prostatic hyperplasia (BPH), also known as enlarged prostate, in men. It helps to relieve symptoms like frequent urination, difficulty starting urination, and weak urine stream. This medicine is not approved to prevent prostate cancer.
Diltiazem works by relaxing blood vessels, which lowers blood pressure. It also reduces the heart's workload, which can prevent chest pain. This medicine blocks calcium from entering heart and blood vessel cells.
This medicine contains two drugs that work in different ways. Dutasteride lowers a hormone called DHT that causes the prostate to grow. Tamsulosin relaxes the muscles in the prostate and bladder, making it easier to urinate.
- • Swelling in your ankles or feet
- • Headache
- • Dizziness
- • Slow heart rate
- • Constipation
- • Problems with ejaculation
- • Impotence (trouble getting or keeping an erection)
- • Decreased sex drive
- • Dizziness
- • Breast enlargement or tenderness
- Shortness of breath 3,200
- Tiredness 2,637
- Feeling sick to your stomach 2,372
- Discomfort 2,364
- Feeling lightheaded 2,089
- Shortness of breath 1,233
- Tiredness 1,142
- Feeling lightheaded or unsteady 986
- Weakness 933
- Loose stools 897
Diltiazem can interact with other heart medications. Tell your doctor if you take beta-blockers or digoxin. Using diltiazem with these drugs can cause heart problems. Your doctor may need to adjust your dosages.
This medicine can cause dizziness, lightheadedness, and fainting, especially when you stand up. Be careful to avoid falls or injuries. Do not take this medicine with other alpha-blockers, as it can lower your blood pressure too much. This medicine can affect your PSA levels, which are used to screen for prostate cancer, so tell your doctor you are taking this medicine. Pregnant women should not handle this medicine, as it can harm a male fetus.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if diltiazem will harm your unborn baby. Diltiazem passes into breast milk, so talk to your doctor about breastfeeding while taking this medicine.
This medicine is not for women. It can harm a male fetus if a pregnant woman is exposed to it. Pregnant women should not handle this medicine.
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How to Read This diltiazem vs dutasteride/tamsulosin Comparison
diltiazem is classified in the Calcium Channel Blocker drug class, while dutasteride/tamsulosin sits within the 5-ARI / Alpha-Blocker Combination class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, diltiazem has 12,662 submissions while dutasteride/tamsulosin has 5,191. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to diltiazem slows down how the body removes dutasteride, which can lead to higher levels of the drug in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between diltiazem and dutasteride/tamsulosin - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.