digoxin vs tamsulosin
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Side-by-side comparison of digoxin and tamsulosin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.6 Digoxin and Theophylline Dosage adjustments are not necessary when a tamsulosin hydrochloride capsules are administered concomitantly with digoxin or theophylline [see Clinical Pharmacology (12.3)].
Lanoxin
Flomax
Digoxin (Lanoxin) is a medicine that helps your heart pump better. It is used to treat heart failure and control irregular heartbeats.
Tamsulosin (Flomax) helps to improve urination in men with enlarged prostate glands. It relaxes the muscles in the prostate and bladder, making it easier to urinate.
Digoxin is used to treat mild to moderate heart failure in adults. It helps the heart pump more blood with each beat. Digoxin is also used in children with heart failure to help their heart work better. In adults, it can control a fast and irregular heartbeat called atrial fibrillation.
This medicine treats the symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). BPH can cause problems with urination, like difficulty starting or stopping the flow of urine. Tamsulosin helps to relieve these symptoms.
Digoxin belongs to a class of drugs called cardiac glycosides. It works by making the heart muscle contract more strongly. It also slows down the electrical signals in the heart, which can help control irregular heartbeats.
Tamsulosin blocks alpha-1 adrenoceptors in the prostate and bladder. These receptors control muscle tightness. By blocking them, tamsulosin relaxes the muscles, which improves urine flow.
- • Nausea
- • Vomiting
- • Diarrhea
- • Dizziness
- • Headache
- • Headache
- • Dizziness
- • Runny nose
- • Infection
- • Abnormal ejaculation
- Dyspnoea 6,065
- Nausea 4,754
- Dizziness 4,439
- Fatigue 4,175
- Atrial Fibrillation 3,974
- Fatigue 1,417
- Dyspnoea 1,332
- Dizziness 1,131
- Diarrhoea 1,121
- Headache 883
Digoxin can cause serious side effects, including dangerous heart rhythms. You are at higher risk if you have certain heart conditions or kidney problems. Tell your doctor right away if you have nausea, vomiting, vision changes, or an irregular heartbeat.
Tamsulosin can cause a sudden drop in blood pressure when you stand up, leading to dizziness or fainting. Avoid situations where you could get hurt if you faint. Tell your eye doctor if you are planning to have cataract or glaucoma surgery, as tamsulosin can cause complications during the procedure. You should be screened for prostate cancer before starting tamsulosin and regularly after.
It is not known if digoxin can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. The medicine passes into breast milk, but it is unlikely to harm the baby.
This medicine is only for men. It is not meant to be used by women. There is no information about the safety of tamsulosin during pregnancy or breastfeeding because it is not used in women.
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How to Read This digoxin vs tamsulosin Comparison
digoxin is classified in the Cardiac Glycoside drug class, while tamsulosin sits within the Alpha-1 Adrenergic Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, digoxin has 23,407 submissions while tamsulosin has 5,884. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to tamsulosin does not interfere with how digoxin works or how much of it stays in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for digoxin or tamsulosin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.