digoxin vs dutasteride/tamsulosin
PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.
Side-by-side comparison of digoxin and dutasteride/tamsulosin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.4 Digoxin and Theophylline Dutasteride Dutasteride does not alter the steady-state pharmacokinetics of digoxin when administered concomitantly at a dose of 0.5 mg/day for 3 weeks [see Clinical Pharmacology ( 12.3 )] . Tamsulosin Dosage adjustments are not necessary when tamsulosin is administered concomitantly with digoxin or theophylline [see Clinical Pharmacology ( 12.3 ) ] .
Lanoxin
Jalyn
Digoxin (Lanoxin) is a medicine that helps your heart pump better. It is used to treat heart failure and control irregular heartbeats.
This medicine combines two drugs to treat enlarged prostate in men. It helps improve urine flow and reduce symptoms.
Digoxin is used to treat mild to moderate heart failure in adults. It helps the heart pump more blood with each beat. Digoxin is also used in children with heart failure to help their heart work better. In adults, it can control a fast and irregular heartbeat called atrial fibrillation.
This medicine treats benign prostatic hyperplasia (BPH), also known as enlarged prostate, in men. It helps to relieve symptoms like frequent urination, difficulty starting urination, and weak urine stream. This medicine is not approved to prevent prostate cancer.
Digoxin belongs to a class of drugs called cardiac glycosides. It works by making the heart muscle contract more strongly. It also slows down the electrical signals in the heart, which can help control irregular heartbeats.
This medicine contains two drugs that work in different ways. Dutasteride lowers a hormone called DHT that causes the prostate to grow. Tamsulosin relaxes the muscles in the prostate and bladder, making it easier to urinate.
- • Nausea
- • Vomiting
- • Diarrhea
- • Dizziness
- • Headache
- • Problems with ejaculation
- • Impotence (trouble getting or keeping an erection)
- • Decreased sex drive
- • Dizziness
- • Breast enlargement or tenderness
- Dyspnoea 6,065
- Nausea 4,754
- Dizziness 4,439
- Fatigue 4,175
- Atrial Fibrillation 3,974
- Shortness of breath 1,233
- Tiredness 1,142
- Feeling lightheaded or unsteady 986
- Weakness 933
- Loose stools 897
Digoxin can cause serious side effects, including dangerous heart rhythms. You are at higher risk if you have certain heart conditions or kidney problems. Tell your doctor right away if you have nausea, vomiting, vision changes, or an irregular heartbeat.
This medicine can cause dizziness, lightheadedness, and fainting, especially when you stand up. Be careful to avoid falls or injuries. Do not take this medicine with other alpha-blockers, as it can lower your blood pressure too much. This medicine can affect your PSA levels, which are used to screen for prostate cancer, so tell your doctor you are taking this medicine. Pregnant women should not handle this medicine, as it can harm a male fetus.
It is not known if digoxin can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. The medicine passes into breast milk, but it is unlikely to harm the baby.
This medicine is not for women. It can harm a male fetus if a pregnant woman is exposed to it. Pregnant women should not handle this medicine.
How to Read This digoxin vs dutasteride/tamsulosin Comparison
digoxin is classified in the Cardiac Glycoside drug class, while dutasteride/tamsulosin sits within the 5-ARI / Alpha-Blocker Combination class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, digoxin has 23,407 submissions while dutasteride/tamsulosin has 5,191. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these medications do not significantly change how the body processes or absorbs each other.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for digoxin or dutasteride/tamsulosin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.