dicloxacillin vs warfarin
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Side-by-side comparison of dicloxacillin and warfarin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Dicloxacillin may reduce the anticoagulant response to dicumarol and warfarin.
Dynapen
Coumadin, Jantoven
Dicloxacillin is an antibiotic that fights bacteria in your body. It belongs to a class of drugs called penicillinase-resistant penicillins.
Warfarin is a medicine that helps prevent blood clots. It is used to treat and prevent dangerous clots from forming in your body.
Dicloxacillin treats infections caused by certain staph bacteria that are resistant to penicillin. Your doctor may order lab tests to identify the bacteria causing your infection. This medicine may be used to start treatment while waiting for lab results.
Warfarin is used to prevent and treat blood clots in your veins and lungs. It can also prevent clots if you have atrial fibrillation (irregular heartbeat) or a replacement heart valve. After a heart attack, it can lower the risk of death, another heart attack, or a stroke.
Dicloxacillin works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to form cell walls. This weakens the bacteria and eventually kills them.
Warfarin works by blocking your body's use of vitamin K. Vitamin K is needed to make blood clotting factors. By blocking vitamin K, warfarin makes your blood less likely to clot.
- • Nausea
- • Vomiting
- • Diarrhea
- • Mouth sores
- • Black or hairy tongue
- • Bleeding from any tissue or organ
- Suspected Transmission Of An Infectious Agent Via Product 13
- Rash 12
- Fatigue 11
- Pruritus 11
- Abdominal Discomfort 9
- International Normalised Ratio Increased 10,276
- Dyspnoea 8,408
- Drug Interaction 6,288
- Fatigue 6,143
- Nausea 5,921
Taking dicloxacillin with too little water or right before bed can cause burning, inflammation, or ulcers in your esophagus.
Warfarin can cause major or fatal bleeding. You must have your blood tested regularly (INR) while taking warfarin. Many things, like other medicines and diet changes, can affect your INR. Tell your doctor about any bleeding and follow their instructions to prevent bleeding.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if dicloxacillin will harm an unborn baby. Small amounts of dicloxacillin may pass into breast milk.
Warfarin can harm your unborn baby, especially during the first three months of pregnancy. Do not take warfarin if you are pregnant, unless you have a mechanical heart valve and your doctor says the benefits outweigh the risks. Talk to your doctor if you are breastfeeding, and watch your baby for bruising or bleeding.
How to Read This dicloxacillin vs warfarin Comparison
dicloxacillin is classified in the Penicillinase-Resistant Penicillin drug class, while warfarin sits within the Vitamin K Antagonist (Anticoagulant) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dicloxacillin has 56 submissions while warfarin has 37,036. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to dicloxacillin can make warfarin less effective at thinning the blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for dicloxacillin or warfarin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.