cyclosporine vs piroxicam
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Side-by-side comparison of cyclosporine and piroxicam. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Cyclosporine Clinical Impact: Concomitant use of piroxicam capsules and cyclosporine may increase cyclosporine’s nephrotoxicity. Intervention: During concomitant use of piroxicam capsules and cyclosporine, monitor patients for signs of worsening renal function.
Neoral, Sandimmune, Restasis
Feldene
Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Piroxicam is a medicine that reduces pain and swelling. It belongs to a class of drugs called NSAIDs.
Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.
Piroxicam helps to relieve the pain and swelling from osteoarthritis and rheumatoid arthritis. Osteoarthritis is a joint problem that usually affects older people. Rheumatoid arthritis is a disease that causes joint pain, swelling, and stiffness.
Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.
Piroxicam works by reducing substances in the body that cause pain and inflammation. It blocks the production of prostaglandins. Prostaglandins contribute to inflammation and pain.
- • Irritation where the drops are applied (8%)
- • Nausea
- • Constipation
- • Gas
- • Abdominal pain
- • Diarrhea
- Eye Irritation 7,786
- Pyrexia 4,064
- Eye Pain 3,808
- Nausea 3,623
- Diarrhoea 3,562
- Drug Hypersensitivity 940
- Rash 874
- Arthralgia 861
- Condition Aggravated 857
- Rheumatoid Arthritis 809
To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.
Piroxicam may increase your risk of serious heart problems like heart attack or stroke, which can be fatal. This risk may happen early in treatment and increase with longer use. Piroxicam can also increase your risk of serious stomach and intestine problems, including bleeding, ulcers, and holes, which can be fatal. You should not take piroxicam if you are having heart bypass surgery.
It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.
Taking piroxicam during the last 3 months of pregnancy may harm your unborn baby. Avoid using piroxicam starting at 30 weeks of pregnancy. Piroxicam may also affect fertility and make it harder to get pregnant.
Also Compare, Nearby Drugs
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How to Read This cyclosporine vs piroxicam Comparison
cyclosporine is classified in the Calcineurin Inhibitor (Immunosuppressant) drug class, while piroxicam sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cyclosporine has 22,843 submissions while piroxicam has 4,341. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to taking piroxicam with cyclosporine can make the cyclosporine more toxic to your kidneys.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for cyclosporine or piroxicam.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.