azilsartan vs valsartan
Side-by-side comparison of azilsartan and valsartan Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Edarbi
Diovan
Edarbyclor is a drug that combines two medicines to lower high blood pressure. It helps reduce the risk of strokes and heart attacks.
Entresto is a medicine that combines two drugs to help adults and children with heart failure. It can lower the risk of death and hospitalization.
Edarbyclor is used to treat high blood pressure. It can be used if one medicine isn't enough to control your blood pressure. It can also be used as the first medicine if you likely need more than one drug. Lowering blood pressure helps prevent strokes and heart attacks.
Entresto is used to treat heart failure in adults and children aged one year and older. It helps people whose hearts don't pump blood well enough. It can reduce hospital visits and the risk of death from heart problems.
Edarbyclor contains two medicines that work in different ways to lower blood pressure. One medicine blocks a substance that tightens blood vessels. The other medicine helps your body get rid of extra salt and water.
Entresto works by blocking two substances in your body that can worsen heart failure. One substance is neprilysin, and the other is angiotensin II. By blocking these, Entresto helps your heart pump blood more easily and reduces strain.
- • Dizziness
- • Fatigue
- • Low blood pressure
- • High potassium levels in your blood
- • Cough
- • Dizziness
- • Kidney problems
No adverse event reports.
- The medicine is not working 6,228
- Feeling tired 5,476
- Feeling lightheaded 5,251
- Difficulty breathing 5,251
- Feeling sick to your stomach 5,164
Edarbyclor can harm your unborn baby. If you are pregnant or become pregnant, stop taking this medicine and tell your doctor right away.
Entresto can harm your unborn baby, even causing death. If you are pregnant or become pregnant, stop taking Entresto right away and tell your doctor.
Edarbyclor can cause harm to an unborn baby, including injury or death. Do not take this medicine if you are pregnant or plan to become pregnant. It is not recommended to breastfeed while taking Edarbyclor.
Entresto can cause serious harm or death to an unborn baby. Do not take this medicine if you are pregnant. Breastfeeding is not recommended while taking Entresto.
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How to Read This azilsartan vs valsartan Comparison
azilsartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while valsartan sits within the Angiotensin II Receptor Blocker (ARB) class. Because both drugs share the same classification, they are often considered interchangeable in theory — but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, azilsartan has 0 submissions while valsartan has 27,370. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between azilsartan and valsartan — always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.