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azilsartan vs irbesartan

Side-by-side comparison of azilsartan and irbesartan. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
azilsartan Angiotensin II Receptor Blocker (ARB)
irbesartan Angiotensin II Receptor Blocker (ARB)
Type
azilsartan Prescription
irbesartan Prescription
Summary
azilsartan

No summary available.

irbesartan

Irbesartan is a medicine that lowers blood pressure. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs).

What It Treats
azilsartan

Information not available.

irbesartan

Irbesartan is used to treat high blood pressure (hypertension). Lowering blood pressure reduces the risk of strokes and heart attacks. It is also used to treat kidney problems caused by diabetes in people with high blood pressure.

How It Works
azilsartan

Information not available.

irbesartan

Irbesartan blocks a substance in your body that tightens blood vessels. This helps blood vessels relax and widens them, which lowers blood pressure. It also helps protect the kidneys in people with diabetes.

Common Side Effects
azilsartan
  • Dizziness
  • Fatigue
irbesartan
  • Diarrhea
  • Heartburn
  • Tiredness
  • Increased potassium levels
  • Dizziness
FAERS Reports
azilsartan

No adverse event reports.

irbesartan
  • Tiredness 2,461
  • Feeling sick to your stomach 2,421
  • Loose or watery stools 2,261
  • Sudden kidney damage 2,054
  • Feeling lightheaded or unsteady 1,983
Serious Warnings
azilsartan

No specific warnings noted.

irbesartan

Irbesartan can harm your unborn baby. If you are pregnant or plan to become pregnant, tell your doctor right away. Stop taking irbesartan as soon as you know you are pregnant.

Pregnancy
azilsartan

No pregnancy information available.

irbesartan

Irbesartan can cause serious harm or death to an unborn baby. Do not take this medicine if you are pregnant. Talk to your doctor if you are breastfeeding, as this medication may not be safe for your baby.

Also Compare, Nearby Drugs

How to Read This azilsartan vs irbesartan Comparison

azilsartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while irbesartan sits within the Angiotensin II Receptor Blocker (ARB) class. Because both drugs share the same classification, they are often considered interchangeable in theory, but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, azilsartan has 0 submissions while irbesartan has 11,180. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between azilsartan and irbesartan - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.