azilsartan vs losartan
Side-by-side comparison of azilsartan and losartan Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Edarbi
Cozaar
Edarbyclor is a drug that combines two medicines to lower high blood pressure. It helps reduce the risk of strokes and heart attacks.
Losartan is a medicine that lowers blood pressure. It can also help prevent strokes in some people with high blood pressure and an enlarged heart.
Edarbyclor is used to treat high blood pressure. It can be used if one medicine isn't enough to control your blood pressure. It can also be used as the first medicine if you likely need more than one drug. Lowering blood pressure helps prevent strokes and heart attacks.
Losartan is used to treat high blood pressure in adults and children over 6 years old. Lowering blood pressure reduces the risk of strokes and heart attacks. It is also used to treat kidney problems in people with type 2 diabetes and high blood pressure. Losartan can also reduce the risk of stroke in patients with high blood pressure and an enlarged left ventricle of the heart.
Edarbyclor contains two medicines that work in different ways to lower blood pressure. One medicine blocks a substance that tightens blood vessels. The other medicine helps your body get rid of extra salt and water.
Losartan blocks a substance in your body that tightens blood vessels. This helps blood vessels relax, which lowers blood pressure. It also helps the kidneys work better in people with diabetes.
- • Dizziness
- • Fatigue
- • Dizziness
- • Upper respiratory infection
- • Nasal congestion
- • Back pain
No adverse event reports.
- Tiredness 11,852
- Diarrhea 9,868
- Feeling sick to your stomach 9,206
- The medicine is not working 9,195
- Difficulty breathing 8,439
Edarbyclor can harm your unborn baby. If you are pregnant or become pregnant, stop taking this medicine and tell your doctor right away.
Losartan can harm your unborn baby, even causing death. If you are pregnant or plan to become pregnant, tell your doctor right away. Stop taking losartan as soon as you know you are pregnant.
Edarbyclor can cause harm to an unborn baby, including injury or death. Do not take this medicine if you are pregnant or plan to become pregnant. It is not recommended to breastfeed while taking Edarbyclor.
Do not take losartan if you are pregnant. It can cause serious harm or death to the developing fetus. If you are breastfeeding, talk to your doctor about whether losartan is right for you.
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How to Read This azilsartan vs losartan Comparison
azilsartan is classified in the Angiotensin II Receptor Blocker (ARB) drug class, while losartan sits within the Angiotensin II Receptor Blocker (ARB) class. Because both drugs share the same classification, they are often considered interchangeable in theory — but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, azilsartan has 0 submissions while losartan has 48,560. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between azilsartan and losartan — always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.