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amikacin vs delafloxacin

Side-by-side comparison of amikacin and delafloxacin Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
amikacin Aminoglycoside Antibiotic
delafloxacin Fluoroquinolone Antibiotic
Type
amikacin Prescription
delafloxacin Prescription
Summary
amikacin

Amikacin is an antibiotic medicine. It fights serious infections caused by certain types of bacteria.

delafloxacin

Baxdela is an antibiotic that fights bacteria in your body. It is used to treat certain skin infections and pneumonia.

What It Treats
amikacin

Amikacin treats serious infections caused by bacteria. This includes infections in the blood, lungs, bones, joints, brain, skin, and abdomen. It can also treat burns, post-surgery infections, and complicated urinary tract infections.

delafloxacin

Baxdela treats acute bacterial skin infections and skin structure infections in adults. It can treat infections caused by bacteria like Staphylococcus aureus (including MRSA), Streptococcus, and others. Baxdela also treats community-acquired bacterial pneumonia in adults, caused by bacteria like Streptococcus pneumoniae, Klebsiella pneumoniae, and others.

How It Works
amikacin

Amikacin belongs to a class of drugs called aminoglycosides. It works by stopping the growth of bacteria. This helps your body fight off the infection.

delafloxacin

Baxdela belongs to a class of drugs called fluoroquinolones. It works by stopping bacteria from multiplying. This helps your body fight off the infection.

Common Side Effects
amikacin

No common side effects listed.

delafloxacin
  • Nausea
  • Diarrhea
  • Headache
  • Changes in liver enzyme tests
  • Vomiting
FAERS Reports
amikacin
  • Off Label Use 1,908
  • Drug Ineffective 1,673
  • Cough 1,620
  • Dyspnoea 1,556
  • Hospitalisation 1,360
delafloxacin

No adverse event reports.

Serious Warnings
amikacin

Amikacin can potentially cause hearing loss and kidney damage. Tell your doctor if you have kidney problems or are taking other medicines that can affect your hearing or kidneys. Your doctor should closely monitor you for hearing and kidney problems during treatment. This drug can also cause muscle weakness or breathing problems, especially if you are also taking anesthesia or certain muscle relaxants.

delafloxacin

Baxdela has a boxed warning. It can cause serious side effects like tendon problems, nerve damage, and central nervous system problems. It can also make muscle weakness worse if you have myasthenia gravis. Stop taking Baxdela right away if you have any of these side effects.

Pregnancy
amikacin

Tell your doctor if you are pregnant or breastfeeding. Amikacin may harm your unborn baby. It is not known if amikacin passes into breast milk.

delafloxacin

It is not known if Baxdela will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if Baxdela passes into breast milk. Talk to your doctor about the best way to feed your baby if you take Baxdela.

Also Compare — Nearby Drugs

How to Read This amikacin vs delafloxacin Comparison

amikacin is classified in the Aminoglycoside Antibiotic drug class, while delafloxacin sits within the Fluoroquinolone Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amikacin has 8,117 submissions while delafloxacin has 0. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between amikacin and delafloxacin — always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.