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Two medicines, side by side

Alirocumab vs carboxymethylcellulose

Alirocumab is labeled for angina, heart attack and coronary artery disease and high cholesterol; carboxymethylcellulose has no indication this site maps. Their labels share no use, so they are not alternatives to each other. Pharmacies paid $258.01 per mL (Praluent 150 mg/mL pen) and $0.267 per unit (Carboxymethylcell 0.5% eye drp) (NADAC, October 7, 2026); the strengths differ and one is a brand and one a generic, so the two prices are not like for like.

Check it at the source: the alirocumab FDA label on DailyMed (effective July 16, 2026); the carboxymethylcellulose FDA label on DailyMed (effective June 30, 2022).

Highlights of the alirocumab record

Alirocumab (Praluent) · label of July 16, 2026

Used for

From the label: indications

PRALUENT ® is indicated: To reduce the risk of major adverse cardiovascular (CV) events (coronary heart disease death, myocardial infarction, stroke, or unstable angina requiring hospitalization) in adults at increased risk for these events. […]

On the market

Earliest approval on file
July 24, 2015
Generic labelers
none listed
Pharmacy cost
$258.01 per mL

Supply and safety

Shortage
No current entry
Recalls
0

Highlights of the carboxymethylcellulose record

Carboxymethylcellulose · label of June 30, 2022

Used for

From the label: indications

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.

On the market

Earliest approval on file
n/a
Generic labelers
none listed
Pharmacy cost
$0.267 per unit

Supply and safety

Shortage
No current entry
Recalls
0

Source: FDA drug labels via openFDA (Alirocumab label of July 16, 2026, Carboxymethylcellulose label of June 30, 2022); NDC Directory, Drugs@FDA, NADAC, FDA shortages and recalls (October 8, 2026)

How do alirocumab and carboxymethylcellulose differ on the record?

AlirocumabCarboxymethylcellulose
Labeled forAngina, Heart attack and coronary artery disease, High cholesteroln/a
Pharmacologic classPCSK9 Inhibitorn/a
How it works (label)Alirocumab is a human monoclonal antibody that binds to proprotein convertase subtilisin kexin type 9 (PCSK9).n/a
Half-life (label)Based on a population pharmacokinetic analysis, the median apparent half-life of alirocumab at steady state was 17 to 20 days in patients receiving alirocumab at subcutaneous doses of 75 mg every 2 weeks or 150 mg every …n/a
Earliest approval on file (Drugs@FDA)July 24, 2015n/a
First generic approvednonenone
Generic labelers (NDC)none listednone listed
Pharmacy cost (NADAC, each one's most listed form; strengths differ)$258.01 per mL (Praluent 150 mg/mL pen)$0.267 per unit (Carboxymethylcell 0.5% eye drp)
12-month price change+3%-30%
Boxed warningNoNo
Shortage nowNo current entryNo current entry
Recalls recorded00
FAERS reports (a report is not proof of cause; counts follow how widely a medicine is used)24,93510,401
DEA schedulenonenone

Source: Drugs@FDA, FDA NDC Directory, CMS NADAC of October 7, 2026, FDA shortages and recalls, FAERS via openFDA (FDA files October 8, 2026)

What next?

Alternatives to alirocumab
every medicine labeled for the same conditions