FDA pharmacologic class
Thiazide diuretics
2 medicines are in FDA's class of thiazide diuretics (thiazide diuretics): hydrochlorothiazide (Inzirqo) and chlorothiazide (Diuril); 19 combination products also contain one. All 21 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is hydrochlorothiazide 25 mg tablet at $0.0115 per tablet (NADAC).
Which medicines are thiazide diuretics?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Hydrochlorothiazide | Inzirqo | 43 labelers | $0.0115 per tablet 25 mg tablet | No | A presentation being discontinued | 7 |
| Hydrochlorothiazide and losartan | Hyzaar | 29 labelers | $0.0762 per tablet 100-12.5 mg tablet | Yes | No current entry | 29 |
| Hydrochlorothiazide and valsartan | Diovan | 18 labelers | $0.101 per tablet 160-12.5 mg tablet | Yes | No current entry | 23 |
| Hydrochlorothiazide and lisinopril | Zestoretic | 27 labelers | $0.0293 per tablet 10-12.5 mg tablet | Yes | No current entry | 7 |
| Hydrochlorothiazide and olmesartan | Benicar | 17 labelers | $0.165 per tablet 20-12.5 mg tablet | Yes | No current entry | 1 |
| Hydrochlorothiazide and triamterene | none listed | 24 labelers | $0.0969 per tablet 37.5-25 mg tablet | No | No current entry | 5 |
| Amlodipine and hydrochlorothiazide and olmesartan | Tribenzor | 8 labelers | $0.776 per unit 20-5-12.5 | Yes | No current entry | 0 |
| Bisoprolol and hydrochlorothiazide | none listed | 11 labelers | $0.209 per tablet 10-6.25 mg tablet | No | No current entry | 4 |
| Amlodipine and hydrochlorothiazide and valsartan | Exforge | 5 labelers | $6.09 per tablet 10-160-25 mg tablet | Yes | No current entry | 0 |
| Hydrochlorothiazide and irbesartan | Avalide | 11 labelers | $0.149 per tablet 150-12.5 mg tablet | Yes | No current entry | 8 |
| Hydrochlorothiazide and telmisartan | Micardis | 8 labelers | $0.357 per tablet 40-12.5 mg tablet | Yes | No current entry | 3 |
| Benazepril and hydrochlorothiazide | Lotensin | 3 labelers | $0.222 per tablet 20-12.5 mg tablet | Yes | No current entry | 0 |
| Candesartan and hydrochlorothiazide | Atacand | 4 labelers | $0.954 per tablet 16-12.5 mg tablet | Yes | No current entry | 2 |
| Hydrochlorothiazide and metoprolol | none listed | 5 labelers | $1.41 per tablet 100-25 mg tablet | No | No current entry | 1 |
| Hydrochlorothiazide and quinapril | none listed | 4 labelers | n/a | Yes | In shortage | 4 |
| Hydrochlorothiazide and spironolactone | none listed | 6 labelers | $0.483 per tablet 25-25 tablet | No | No current entry | 0 |
| Chlorothiazide | Diuril | 5 labelers | n/a | No | A presentation being discontinued | 0 |
| Enalapril and hydrochlorothiazide | Vaseretic | 2 labelers | $0.209 per tablet 10-25 mg tablet | Yes | No current entry | 2 |
| Captopril and hydrochlorothiazide | none listed | 1 labeler | n/a | Yes | No current entry | 0 |
| Fosinopril and hydrochlorothiazide | none listed | 2 labelers | $0.634 per tablet 10-12.5 mg tablet | Yes | No current entry | 1 |
| Amiloride and hydrochlorothiazide | none listed | 1 labeler | $0.450 per tablet 5-50 mg tablet | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price