FDA pharmacologic class
Potassium-sparing Diuretic
2 medicines are in FDA's class of potassium-sparing diuretics: triamterene (Dyrenium) and amiloride; 2 combination products also contain one. All 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is triamterene-hydrochlorothiazide 37.5-25 mg tablet at $0.0969 per tablet (NADAC).
Which medicines are potassium-sparing diuretic?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Hydrochlorothiazide and triamterene | none listed | 24 labelers | $0.0969 per tablet 37.5-25 mg tablet | No | No current entry | 5 |
| Triamterene | Dyrenium | 3 labelers | $5.98 per capsule 50 mg capsule | Yes | No current entry | 0 |
| Amiloride | none listed | 2 labelers | $0.190 per tablet 5 mg tablet | Yes | No current entry | 0 |
| Amiloride and hydrochlorothiazide | none listed | 1 labeler | $0.450 per tablet 5-50 mg tablet | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price