FDA pharmacologic class
Polyene Antifungal
2 medicines are in FDA's class of polyene antifungals: nystatin (Klayesta) and amphotericin b; 1 combination product also contains one. All 3 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is nystatin 100,000 unit/g cream at $0.175 per gram (NADAC).
Which medicines are polyene antifungal?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Nystatin | Nystop, Klayesta, Mycostatin | 40 labelers | $0.175 per gram 100,000 unit/g cream | No | No current entry | 18 |
| Nystatin and triamcinolone | none listed | 18 labelers | $0.225 per gram Nystatin-triamcinolone cream | No | No current entry | 4 |
| Amphotericin b | none listed | 5 labelers | n/a | No | No current entry | 1 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price