Skip to main content

FDA pharmacologic class

Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor

3 medicines are in FDA's class of human immunodeficiency virus integrase strand transfer inhibitors: raltegravir (Isentress), dolutegravir (Tivicay) and cabotegravir (Apretude); 5 combination products also contain one. 1 of the 8 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is isentress 400 mg tablet at $34.54 per tablet (NADAC).

Which medicines are human immunodeficiency virus integrase strand transfer inhibitor?

Recalls: FDA enforcement reports, 2012 on
MedicineBrand namesGeneric labelers (all forms)Pharmacy costBoxed warningShortageRecalls since 2012
RaltegravirIsentress1 labeler$34.54 per tablet 400 mg tabletNoNo current entry0
DolutegravirTivicaynone listed$77.64 per tablet 50 mg tabletNoNo current entry3
CabotegravirApretude, Vocabrianone listedn/aYesNo current entry0
Abacavir and dolutegravir and lamivudineTriumeqnone listed$130.01 per tablet 600-50-300 mg tabletYesNo current entry1
Cobicistat, elvitegravir, emtricitabine and tenofovir alafenamideGenvoyanone listed$143.35 per tablet Genvoya tabletYesNo current entry0
Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxilStribildnone listed$150.14 per tablet Stribild tabletYesNo current entry0
Dolutegravir and lamivudineDovatonone listed$105.22 per tablet 50-300 mg tabletYesNo current entry0
Dolutegravir and rilpivirineJulucanone listed$121.87 per tablet 50-25 mg tabletNoNo current entry0

Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)

What do pharmacies pay?

Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?