FDA pharmacologic class
Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor
1 medicine is in FDA's class of hepatitis c virus nucleotide analog ns5b polymerase inhibitors: sofosbuvir (Sovaldi); 3 combination products also contain one. 0 of the 4 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is sofosbuvir-velpatasvir 400-100 at $278.03 per unit (NADAC).
Which medicines are hepatitis c virus nucleotide analog ns5b polymerase inhibitor?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Ledipasvir and sofosbuvir | Harvoni | none listed | n/a | Yes | No current entry | 0 |
| Sofosbuvir and velpatasvir | Epclusa | none listed | $278.03 per unit 400-100 | Yes | No current entry | 1 |
| Sofosbuvir | Sovaldi | none listed | n/a | Yes | No current entry | 0 |
| Sofosbuvir and velpatasvir and voxilaprevir | Vosevi | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price