FDA pharmacologic class
Benzodiazepines
14 medicines are in FDA's class of benzodiazepines (benzodiazepines): lorazepam (Ativan), clonazepam (Klonopin), alprazolam (Xanax), diazepam (Valium), temazepam (Restoril), midazolam (Nayzilam), clobazam (Onfi), chlordiazepoxide and 6 more; 2 combination products also contain one. 15 of the 16 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is alprazolam 0.25 mg tablet at $0.0236 per tablet (NADAC).
Which medicines are benzodiazepines?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Lorazepam | Ativan, Loreev | 36 labelers | $0.0344 per tablet 0.5 mg tablet | Yes | In shortage | 8 |
| Clonazepam | Klonopin | 31 labelers | $0.0244 per tablet 1 mg tablet | Yes | In shortage | 7 |
| Alprazolam | Xanax | 30 labelers | $0.0236 per tablet 0.25 mg tablet | Yes | No current entry | 23 |
| Diazepam | Valium, Valtoco | 45 labelers | $0.0283 per tablet 10 mg tablet | Yes | No current entry | 8 |
| Temazepam | Restoril | 20 labelers | $0.0767 per capsule 15 mg capsule | Yes | No current entry | 1 |
| Midazolam | Nayzilam | 22 labelers | $0.233 per mL 2 mg/2 mL vial | Yes | In shortage | 19 |
| Clobazam | Sympazan, Onfi | 16 labelers | $0.243 per tablet 10 mg tablet | Yes | No current entry | 7 |
| Chlordiazepoxide | none listed | 15 labelers | $0.158 per capsule 25 mg capsule | Yes | No current entry | 0 |
| Clorazepate | none listed | 8 labelers | $0.524 per tablet 3.75 mg tablet | Yes | No current entry | 2 |
| Chlordiazepoxide and clidinium | Librax | 12 labelers | $0.256 per capsule Chlordiazepoxide-clidinium capsule | Yes | No current entry | 2 |
| Oxazepam | none listed | 6 labelers | $0.725 per capsule 10 mg capsule | Yes | No current entry | 0 |
| Triazolam | none listed | 7 labelers | $0.308 per tablet 0.25 mg tablet | Yes | No current entry | 0 |
| Estazolam | none listed | 3 labelers | $0.839 per tablet 2 mg tablet | Yes | No current entry | 0 |
| Amitriptyline and chlordiazepoxide | none listed | 1 labeler | $1.20 per unit 5-12.5 | Yes | No current entry | 0 |
| Flurazepam | none listed | 1 labeler | n/a | Yes | In shortage | 0 |
| Quazepam | none listed | none listed | n/a | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price