FDA pharmacologic class
Antiarrhythmic
12 medicines are in FDA's class of antiarrhythmics: lidocaine (Xylocaine), sotalol (Betapace), amiodarone (Pacerone), flecainide, propafenone, mexiletine, dofetilide (Tikosyn), procainamide and 4 more; 5 combination products also contain one. 14 of the 17 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is sotalol 80 mg tablet at $0.0707 per tablet (NADAC).
Which medicines are antiarrhythmic?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Lidocaine | Xylocaine, Lidoderm, Ztlido | 81 labelers | $0.154 per gram 5% ointment | No | In shortage | 39 |
| Sotalol | Betapace, Sotylize | 18 labelers | $0.0707 per tablet 80 mg tablet | Yes | No current entry | 1 |
| Amiodarone | Nexterone, Pacerone | 32 labelers | $0.122 per tablet 200 mg tablet | Yes | No current entry | 7 |
| Epinephrine and lidocaine | Xylocaine, Xylocaine-Mpf, Flavalta | 17 labelers | $0.139 per mL 1%-epi 1:100,000 | No | In shortage | 9 |
| Flecainide | none listed | 15 labelers | $0.171 per tablet 100 mg tablet | No | No current entry | 2 |
| Propafenone | none listed | 14 labelers | $0.115 per tablet 150 mg tablet | Yes | No current entry | 5 |
| Mexiletine | none listed | 14 labelers | $0.222 per capsule 150 mg capsule | No | No current entry | 0 |
| Dofetilide | Tikosyn | 12 labelers | $0.203 per capsule 125 mcg capsule | Yes | No current entry | 6 |
| Lidocaine and prilocaine | Oraqix | 12 labelers | $0.232 per gram 2.5%-2.5% cream | No | No current entry | 1 |
| Procainamide | none listed | 11 labelers | n/a | Yes | No current entry | 0 |
| Disopyramide | Norpace | 2 labelers | $0.801 per capsule 100 mg capsule | Yes | A presentation being discontinued | 3 |
| Dextromethorphan and quinidine | Nuedexta | 4 labelers | $26.64 per capsule 20-10 mg capsule | No | No current entry | 1 |
| Quinidine | none listed | 4 labelers | $4.92 per tablet 324 mg tablet | Yes | No current entry | 1 |
| Dextrose and lidocaine | none listed | none listed | n/a | No | Listed; available | 0 |
| Ibutilide | Corvert | 1 labeler | n/a | Yes | No current entry | 0 |
| Dronedarone | Multaq | none listed | $13.19 per tablet 400 mg tablet | Yes | No current entry | 0 |
| Lidocaine and tetracaine | Pliaglis | none listed | n/a | No | No current entry | 1 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price