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Medicines labeled for the same conditions

Alternatives to tobramycin

8 other medicines are given the same way (ophthalmic) and in the same FDA class as tobramycin or labeled mainly for the same use (bacterial infections); 4 are in its class, aminoglycoside antibacterials: dexamethasone and neomycin and polymyxin b, gentamicin, bacitracin, hydrocortisone, neomycin and polymyxin b and hydrocortisone and neomycin and polymyxin b; the others include 1 quinolone antimicrobial, 1 dihydrofolate reductase inhibitor antibacterial and 1 sulfonamide antibacterial (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.790 per mL (Gentamicin 0.3% eye drop) (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as tobramycin?

Bacterial infections lists all 51 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (ophthalmic)Pharmacy costBoxed warningShortage
Tobramycinaminoglycoside antibacterialthis medicine18 labelers$1.08 per mL 300 mg/5 mL ampuleNoA presentation being discontinued
Dexamethasone and neomycin and polymyxin bpolymyxin-class antibacterial · same classBacterial infections9 labelers$1.78 per mL Neomyc-polym-dexameth eye dropNoNo current entry
Gentamicinaminoglycoside antibacterial · same classBacterial infections10 labelers$0.790 per mL 0.3% eye dropNoNo current entry
Bacitracin, hydrocortisone, neomycin and polymyxin bpolymyxin-class antibacterial · same classBacterial infections1 labeler$5.52 per gram Neo-bacit-poly-hc eye ointmentNoNo current entry
Hydrocortisone and neomycin and polymyxin bpolymyxin-class antibacterial · same classBacterial infections1 labeler$17.64 per mL Neomycin-poly-hc eye dropsNoNo current entry
Ofloxacinquinolone antimicrobialBacterial infections23 labelers$1.24 per mL 0.3% eye dropsNoNo current entry
Polymyxin b and trimethoprimdihydrofolate reductase inhibitor antibacterialBacterial infections10 labelers$0.452 per mL Polymyxin b-tmp eye dropsNoNo current entry
Sulfacetamidesulfonamide antibacterialBacterial infections6 labelers$1.96 per mL 10% eye dropsNoNo current entry
Azithromycinmacrolide antimicrobialBacterial infectionsnone listed$98.51 per mL 1% eye dropsNoA presentation being discontinued

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

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