Medicines labeled for the same conditions
Alternatives to tizanidine
8 other medicines are given the same way (oral) and in the same FDA class as tizanidine or labeled mainly for the same use (muscle spasms and spasticity); the others include 6 muscle relaxants, 1 gamma-aminobutyric acid-ergic agonist and 1 skeletal muscle relaxant (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as tizanidine?
Muscle spasms and spasticity lists all 12 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Tizanidinecentral alpha-2 adrenergic agonist | this medicine | 51 labelers | $0.0331 per tablet 4 mg tablet | No | No current entry |
| Cyclobenzaprinemuscle relaxant | Muscle spasms and spasticity | 60 labelers | $0.0171 per tablet 10 mg tablet | No | No current entry |
| Baclofengamma-aminobutyric acid-ergic agonist | Muscle spasms and spasticity | 52 labelers | $0.032 per tablet 10 mg tablet | No | No current entry |
| Methocarbamolmuscle relaxant | Muscle spasms and spasticity | 54 labelers | $0.0395 per tablet 500 mg tablet | No | No current entry |
| Metaxalonemuscle relaxant | Muscle spasms and spasticity | 33 labelers | $0.452 per tablet 800 mg tablet | No | No current entry |
| Carisoprodolmuscle relaxant | Muscle spasms and spasticity | 24 labelers | $0.0706 per tablet 350 mg tablet | No | No current entry |
| Chlorzoxazonemuscle relaxant | Muscle spasms and spasticity | 19 labelers | $0.210 per tablet 500 mg tablet | No | No current entry |
| Dantroleneskeletal muscle relaxant | Muscle spasms and spasticity | 7 labelers | $0.409 per capsule 25 mg capsule | Yes | No current entry |
| Orphenadrinemuscle relaxant | Muscle spasms and spasticity | 14 labelers | $0.454 per tablet 100 mg tablet | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Tizanidine: the full record
- label, generics, price, shortages, recalls
- Cyclobenzaprine vs tizanidine
- two records side by side
- Baclofen vs tizanidine
- two records side by side
- Methocarbamol vs tizanidine
- two records side by side
- Metaxalone vs tizanidine
- two records side by side