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teriparatide

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Brand names: Forteo

Parathyroid Hormone Analog Rx

Teriparatide (Forteo) is a medicine that helps to strengthen your bones. It is similar to a natural hormone in your body that helps build bone.

Drug Pricing (NADAC)

Brand Price

$1726.47/unit

Generic Price

$832.72/unit

Generic Savings

52%

Generic Available

Yes (3 manufacturers)

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

What it does

This medicine treats osteoporosis in women after menopause who have a high chance of breaking a bone.

Common side effects

Joint pain, General pain, Feeling sick to your stomach (nausea)

Key warnings

This medicine may increase your risk of a type of bone cancer called osteosarcoma.

How It Works

Teriparatide works like a hormone called parathyroid hormone. This hormone helps your body build new bone. By building new bone, this medicine helps make your bones stronger and less likely to break.

How to Take It

You will inject 20 mcg of this medicine under your skin once a day. You can inject it into your thigh or stomach area. If you feel dizzy when you first start taking it, sit or lie down. Make sure you get enough calcium and vitamin D every day.

Pregnancy & Breastfeeding

It is not known if this medicine will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Breastfeeding is not recommended while using this medicine.

Missed Dose

If you miss a dose, take it as soon as you remember that day. Do not take two doses at once.

Storage

Keep this medicine in the refrigerator at all times and throw away the pen 28 days after you first use it.

Side Effects (from patient reports)

Based on 74,060 FDA adverse event reports.

Feeling sick to your stomach
8,958
Joint pain
8,658
Pain in your arms or legs
8,339
Feeling lightheaded or unsteady
8,265
Accidental fall
7,872
General pain
7,519
Feeling tired or weak
7,158
Pain in your back
5,903
Muscle cramps or twitches
5,730
General feeling of discomfort or illness
5,658

FDA Adverse Event Report Analysis

Detailed analysis of 111,257 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2004–2025.

Total Reports

111,257

Death-Related Reports

5,261

Hospitalization Reports

23,997

Top Indication

Osteoporosis

Gender Distribution

Female 99,360 (91%)
Male 10,239 (9%)

Age Distribution

0–17 63
18–44 1,153
45–64 15,718
65–74 18,058
75+ 25,089

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 NAUSEA 8,956
2 ARTHRALGIA 8,658
3 PAIN IN EXTREMITY 8,338
4 DIZZINESS 8,265
5 FALL 7,872
6 PAIN 7,516
7 FATIGUE 7,159
8 BACK PAIN 5,903
9 MUSCLE SPASMS 5,730
10 MALAISE 5,658
11 HEADACHE 5,461
12 ASTHENIA 5,426
13 INJECTION SITE ERYTHEMA 5,042
14 INJECTION SITE PAIN 4,807
15 INJECTION SITE BRUISING 4,762

Reactions in Death Reports

DEATH 2,901
PNEUMONIA 401
FALL 263
MYOCARDIAL INFARCTION 192
DYSPNOEA 162
CEREBROVASCULAR ACCIDENT 161
RENAL FAILURE 160
RESPIRATORY FAILURE 155
CARDIAC ARREST 149
ASTHENIA 139

Reactions in Hospitalization Reports

FALL 3,935
PNEUMONIA 1,575
HOSPITALISATION 1,503
ASTHENIA 1,397
PAIN 1,383
MALAISE 1,349
BACK PAIN 1,318
NAUSEA 1,299
DIZZINESS 1,192
PAIN IN EXTREMITY 1,127

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

This medicine may increase your risk of a type of bone cancer called osteosarcoma. You should not use this medicine if you have certain bone conditions, such as Paget's disease, bone cancer, or have had radiation to your bones. If you have high calcium levels in your blood, talk to your doctor before taking this medicine.

Known Drug Interactions

minor digoxin

Parathyroid Hormone Analog Teriparatide Sporadic case reports have suggested that hypercalcemia may predispose patients to digitalis toxicity. Teriparatide transiently increases serum calcium.

Mechanism: Teriparatide raises calcium levels in your blood, which can make the heart more sensitive to digoxin and lead to toxic effects.

What to do: Your doctor should monitor your calcium levels and watch for signs of digoxin side effects.

Common Questions

How long can I use teriparatide?
You should only use teriparatide for up to 2 years during your lifetime, unless your doctor says you still have a high risk of breaking a bone.
What should I do if the solution looks cloudy?
Do not use the medicine if the solution has solid particles or is cloudy or colored. It should be clear and colorless.
Can I inject this medicine into my muscle?
No, this medicine is only for injection under the skin (subcutaneous).
What if I have kidney stones?
Tell your doctor if you have kidney stones, as this medicine could make them worse.
Can this medicine affect my heart?
This medicine can cause a temporary drop in blood pressure when you first start taking it. Be careful when standing up.
What if I am taking digoxin?
Tell your doctor if you are taking digoxin, a heart medicine, as this medicine can affect how digoxin works.
Can children use this medicine?
No, this medicine is not approved for use in children.
What do I do if the pen seems to be malfunctioning?
Each pen contains extra volume to allow troubleshooting of the device 2 times.
Does this medicine cause allergic reactions?
In rare cases, some people have had severe allergic reactions to teriparatide. Seek immediate medical attention if you experience swelling or difficulty breathing.
What if I recognize I am pregnant while using this medicine?
Consider discontinuing teriparatide injection when pregnancy is recognized.
What are the common side effects of teriparatide?
The most commonly reported side effects of teriparatide include Joint pain, General pain, Feeling sick to your stomach (nausea). Based on 74,060 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
Does teriparatide interact with other medications?
Yes, teriparatide has 1 known drug interactions. Notable interactions include digoxin. Always inform your doctor about all medications you are taking.
What drug class is teriparatide?
teriparatide belongs to the Parathyroid Hormone Analog drug class. It requires a prescription (Rx). This medicine treats osteoporosis in women after menopause who have a high chance of breaking a bone.
Is there a generic version of teriparatide?
Yes, generic teriparatide is available from 3 manufacturers. The generic costs $832.72 per unit compared to $1726.47 for the brand version, saving approximately 52%. Pricing is based on NADAC (National Average Drug Acquisition Cost) data from CMS.
Is teriparatide safe during pregnancy?
It is not known if this medicine will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

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Medication Guides

Related Health & Safety Data

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What the FDA Data Shows for teriparatide

The FDA label for teriparatide (sold under brand names such as Forteo) classifies it as a prescription-only medication in the Parathyroid Hormone Analog class. This medicine treats osteoporosis in women after menopause who have a high chance of breaking a bone. Official labeling lists 3 commonly reported side effects, including Joint pain, General pain, Feeling sick to your stomach (nausea).

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 74,060 voluntary reports. The database also lists 1 documented drug interaction derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS shows a generic unit cost of $832.72 versus $1726.47 for the brand — a 52% generic savings.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: May 27, 2025

All federal data sources used on this page