Medicines labeled for the same conditions
Alternatives to rifaximin
11 other medicines are given the same way (oral) and in the same FDA class as rifaximin or labeled mainly for the same use (diarrhea); the others include 3 antidiarrheals, 2 opioid agonists and 1 fluoroquinolone antibacterial (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as rifaximin?
Diarrhea lists all 16 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Rifaximinrifamycin antibacterial | this medicine | none listed | n/a | No | No current entry |
| Bismuth subsalicylate | Diarrhea | none listed | $0.0817 per tablet 262 mg tablet chewable | No | No current entry |
| Loperamideopioid agonist | Diarrhea | 98 labelers | $0.0549 per capsule 2 mg capsule | Yes | No current entry |
| Ciprofloxacinfluoroquinolone antibacterial | Diarrhea | 46 labelers | $0.123 per tablet 500 mg tablet | Yes | No current entry |
| Dimethicone and loperamideopioid agonist | Diarrhea | 33 labelers | $0.286 per unit Gs anti-diarrheal-antigas cplt | No | No current entry |
| Atropine and diphenoxylateantidiarrheal | Diarrhea | 19 labelers | $0.139 per tablet 2.5-0.025 mg tablet | No | No current entry |
| Nitazoxanideantiprotozoal | Diarrhea | 4 labelers | $82.20 per tablet 500 mg tablet | No | No current entry |
| Eluxadolinemu-opioid receptor agonist | Irritable bowel syndrome, Diarrhea | none listed | $28.09 per tablet 100 mg tablet | No | No current entry |
| Atropine and difenoxinantidiarrheal | Diarrhea | none listed | $6.91 per tablet 1-0.025 mg tablet | No | No current entry |
| Octreotidesomatostatin analog | Diarrhea | none listed | n/a | No | No current entry |
| Telotristattryptophan hydroxylase inhibitor | Diarrhea | none listed | n/a | No | No current entry |
| Crofelemerantidiarrheal | Diarrhea | none listed | n/a | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Rifaximin: the full record
- label, generics, price, shortages, recalls