Medicines labeled for the same conditions
Alternatives to palonosetron
3 other medicines are given the same way (intravenous) and in the same FDA class as palonosetron or labeled mainly for the same use (nausea and vomiting); 1 is in its class, serotonin-3 receptor antagonists: granisetron; the others include 1 substance p/neurokinin-1 receptor antagonist and 1 dopamine-2 receptor antagonist (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as palonosetron?
Nausea and vomiting lists all 16 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (intravenous) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Palonosetronserotonin-3 receptor antagonist | this medicine | 14 labelers | n/a | No | A presentation being discontinued |
| Granisetronserotonin-3 receptor antagonist · same class | Nausea and vomiting | 4 labelers | n/a | No | No current entry |
| Aprepitantsubstance p/neurokinin-1 receptor antagonist | Nausea and vomiting | none listed | n/a | No | A presentation being discontinued |
| Amisulpridedopamine-2 receptor antagonist | Nausea and vomiting | none listed | n/a | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Palonosetron: the full record
- label, generics, price, shortages, recalls
- Granisetron vs palonosetron
- two records side by side