Alternatives to metaxalone
3 same-class SPL records vs metaxalone - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Skelaxin
About metaxalone
Metaxalone is a muscle relaxant. It helps relieve discomfort from painful muscle and bone problems.
Used for: Metaxalone treats the pain and discomfort caused by muscle problems. It is used along with rest and physical therapy. It does not directly relax your muscles, but it can make you feel sleepy, which may help.
3 Muscle Relaxant peers (wide set)
chlorzoxazone
RxParafon Forte
This medicine treats discomfort from muscle problems. It is used with rest and physical therapy. It helps with acute, painful muscle and bone conditions.
cyclobenzaprine
RxFlexeril, Amrix
This medicine treats muscle spasms caused by painful conditions. It is meant to be used with rest and physical therapy. It should only be used for a short time, usually 2 to 3 weeks.
methocarbamol
RxRobaxin
This medicine treats the discomfort caused by painful muscle problems. It is used along with rest and physical therapy. It does not directly relax your muscles.
metaxalone vs chlorzoxazone & cyclobenzaprine · FAERS reaction fields
FAERS top-reaction field "Pain" shows the widest count spread between metaxalone and chlorzoxazone, cyclobenzaprine, methocarbamol in this extract (4,676-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | metaxalone | chlorzoxazone | cyclobenzaprine | methocarbamol |
|---|---|---|---|---|
| Completed Suicide | 261 | 43 | 1,953 | - |
| Fatigue | 196 | 92 | 3,808 | 1,531 |
| Pain | 195 | 90 | 4,871 | 1,639 |
| Nausea | 190 | 94 | 3,303 | 1,565 |
| Headache | 166 | 72 | 3,292 | 1,201 |
| Toxicity To Various Agents | 163 | - | 2,289 | - |
| Fall | 161 | 45 | 2,334 | 1,046 |
| Diarrhoea | 132 | 53 | 2,426 | 1,078 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
metaxalone peer mix vs class inventory
Peer mix
0 OTC and 3 Rx SPL records in this peer set (3 total). Class inventory for Muscle Relaxant: 4 drugs.
Frequently Asked Questions
What same-class SPL records sit beside metaxalone? ▼
Reading a wide Muscle Relaxant peer set (3 records)
metaxalone (Skelaxin) sits in a wide Muscle Relaxant peer set (3 of 3 class peers shown). Labeled indication field for metaxalone: Metaxalone treats the pain and discomfort caused by muscle problems.
Top FAERS reaction fields for metaxalone total 1,698 reports across 10 reactions, set beside chlorzoxazone, cyclobenzaprine, methocarbamol. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for metaxalone: see also the generic vs brand label guide when reading Skelaxin SPL strings.
Read our methodology - how this data is sourced, computed, and verified.