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Medicines labeled for the same conditions

Alternatives to mesalamine

4 other medicines are given the same way (oral) and in the same FDA class as mesalamine or labeled mainly for the same use (crohn's disease and ulcerative colitis); 3 are in its class, aminosalicylates: sulfasalazine, balsalazide and olsalazine; the others include 1 sphingosine 1-phosphate receptor modulator (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.199 per sulfasalazine 500 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as mesalamine?

Crohn's disease and ulcerative colitis lists all 29 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Mesalamineaminosalicylatethis medicine27 labelers$0.781 per tablet 1.2 g tabletNoA presentation being discontinued
Sulfasalazineaminosalicylate · same classCrohn's disease and ulcerative colitis5 labelers$0.199 per tablet 500 mg tabletNoNo current entry
Balsalazideaminosalicylate · same classCrohn's disease and ulcerative colitis9 labelers$0.344 per capsule 750 mg capsuleNoNo current entry
Olsalazineaminosalicylate · same classCrohn's disease and ulcerative colitisnone listed$15.70 per capsule 250 mg capsuleNoNo current entry
Etrasimod argininesphingosine 1-phosphate receptor modulatorCrohn's disease and ulcerative colitisnone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Mesalamine: the full record
label, generics, price, shortages, recalls
Mesalamine vs sulfasalazine
two records side by side