Alternatives to linaclotide
1 same-class SPL records vs linaclotide - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Linzess
About linaclotide
Linzess is a medicine that helps treat certain bowel problems. It works by helping your bowels move more regularly.
Used for: Linzess is used to treat irritable bowel syndrome with constipation (IBS-C) in adults and children ages 7 and older. It also treats chronic idiopathic constipation (CIC) in adults. Linzess can also treat functional constipation (FC) in children ages 6 and older.
1 Guanylate Cyclase-C Agonist peers (wide set)
linaclotide vs plecanatide · FAERS reaction fields
FAERS top-reaction field "Diarrhoea" shows the widest count spread between linaclotide and plecanatide in this extract (4,139-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | linaclotide | plecanatide |
|---|---|---|
| Diarrhoea | 4,502 | 363 |
| Constipation | 1,862 | 152 |
| Nausea | 1,373 | 159 |
| Fatigue | 1,111 | 106 |
| Abdominal Distension | 1,100 | 100 |
| Abdominal Pain | 1,009 | 96 |
| Headache | 982 | 96 |
| Pain | 896 | 95 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
linaclotide peer mix vs class inventory
Peer mix
0 OTC and 1 Rx SPL records in this peer set (1 total). Class inventory for Guanylate Cyclase-C Agonist: 2 drugs.
Frequently Asked Questions
What same-class SPL records sit beside linaclotide? ▼
Reading a wide Guanylate Cyclase-C Agonist peer set (1 records)
linaclotide (Linzess) sits in a wide Guanylate Cyclase-C Agonist peer set (1 of 1 class peers shown). Labeled indication field for linaclotide: Linzess is used to treat irritable bowel syndrome with constipation (IBS-C) in adults and children ages 7 and older.
Top FAERS reaction fields for linaclotide total 14,515 reports across 10 reactions, set beside plecanatide. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for linaclotide: see also the generic vs brand label guide when reading Linzess SPL strings.
Read our methodology - how this data is sourced, computed, and verified.