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Medicines labeled for the same conditions

Alternatives to dihydroergotamine

3 other medicines are given the same way (nasal) and in the same FDA class as dihydroergotamine or labeled mainly for the same use (migraine); the others include 2 serotonin-1b and serotonin-1d receptor agonists and 1 calcitonin gene-related peptide receptor antagonist (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as dihydroergotamine?

Migraine lists all 27 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (nasal)Pharmacy costBoxed warningShortage
Dihydroergotamineergotamine derivativethis medicine5 labelers$29.44 per mL 4 mg/mL nasal sprayYesNo current entry
Sumatriptanserotonin-1b and serotonin-1d receptor agonistMigraine5 labelers$16.51 per unit 20 mg nasal sprayNoNo current entry
Zolmitriptanserotonin-1b and serotonin-1d receptor agonistMigraine2 labelers$44.04 per unit 5 mg nasal sprayNoNo current entry
Zavegepantcalcitonin gene-related peptide receptor antagonistMigrainenone listed$189.80 per unit 10 mg nasal sprayNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Dihydroergotamine: the full record
label, generics, price, shortages, recalls
Dihydroergotamine vs zolmitriptan
two records side by side