FDA data Registry peer set 11 peers

Alternatives to asenapine

11 same-class SPL records vs asenapine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.

Brand: Saphris

Atypical Antipsychotic Prescription 11 alternatives found

About asenapine

Asenapine (Saphris) is an antipsychotic medicine. It is used to treat bipolar I disorder in adults and children ages 10-17.

Used for: Asenapine is used to treat bipolar I disorder. In children ages 10 to 17, it can treat manic or mixed episodes on its own. In adults, it can be used with lithium or valproate to treat these episodes.

11 Atypical Antipsychotic peers (wide set)

aripiprazole

Rx

Abilify

Aripiprazole is used to treat schizophrenia in adults and teens. It also treats irritability in children with autism. Additionally, it can treat Tourette's disorder.

brexpiprazole

Rx

Rexulti

Rexulti can be used with antidepressants to treat major depressive disorder in adults. It can also treat schizophrenia in adults and children 13 years and older. Additionally, Rexulti can help manage agitation in people with dementia due to Alzheimer's disease. Rexulti should not be used as needed for agitation related to dementia.

cariprazine

Rx

Vraylar

Vraylar can treat schizophrenia in adults and kids 13 and older. It also treats manic or mixed episodes of bipolar I disorder in adults and kids 10 and older. In adults, Vraylar treats the depressive episodes of bipolar I disorder. Vraylar can also be used with antidepressants to treat major depressive disorder in adults.

clozapine

Rx

Clozaril

Versacloz is used to treat schizophrenia in people who haven't responded well to other antipsychotic medicines. Schizophrenia is a mental illness that can cause hallucinations, delusions, and disorganized thinking. Versacloz can also help lower the risk of repeated suicidal behavior in people with schizophrenia or schizoaffective disorder who are at high risk.

iloperidone

Rx

Fanapt

Fanapt is used to treat schizophrenia in adults. Schizophrenia can cause confused thinking, hallucinations, and changes in behavior. Fanapt is also used for the short-term treatment of manic or mixed episodes linked to bipolar I disorder in adults.

lurasidone

Rx

Latuda

Lurasidone is used to treat schizophrenia in adults and teens ages 13-17. It also treats the depressive phase of bipolar disorder in adults and children ages 10-17. In adults, it can be used alone or with lithium or valproate for bipolar depression.

olanzapine

Rx

Zyprexa

Olanzapine is used to treat schizophrenia in adults and teens (13-17). It also treats manic or mixed episodes of bipolar I disorder in adults and teens (13-17). In adults, it can be used with other medicines to treat bipolar depression.

paliperidone

Rx

Invega

This medicine is used to treat schizophrenia in adults and teens (12-17 years old). It can also treat schizoaffective disorder in adults, either alone or with other medicines like mood stabilizers or antidepressants. Schizophrenia can cause hallucinations, delusions, and confused thinking. Schizoaffective disorder includes symptoms of both schizophrenia and mood disorders.

quetiapine

Rx

Seroquel

Quetiapine is used to treat schizophrenia in adults and teens (13-17 years old). It also treats manic and depressive episodes of bipolar disorder in adults and children (10-17 years old). For bipolar disorder, it can be used alone or with other medicines like lithium or divalproex.

risperidone

Rx

Risperdal

Risperidone is used to treat schizophrenia in adults and teens. It also treats manic or mixed episodes of bipolar I disorder, either alone or with lithium or valproate. Additionally, it can help with irritability, including aggression and self-injury, in children and teens with autism.

ziprasidone

Rx

Geodon

Ziprasidone treats schizophrenia in adults. It also treats manic or mixed episodes of bipolar I disorder, either alone or with lithium or valproate. This medicine can help manage mood swings and improve overall mental well-being.

Compare asenapine vs aripiprazole side-by-side →

asenapine vs aripiprazole & brexpiprazole · FAERS reaction fields

FAERS top-reaction field "Drug Interaction" shows the widest count spread between asenapine and aripiprazole, brexpiprazole, cariprazine in this extract (3,511-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.

Side Effect asenapine aripiprazolebrexpiprazolecariprazine
Drug Interaction 78 3,589 - 195
Toxicity To Various Agents 64 - - -
Completed Suicide 61 - - -
Myocarditis 53 - - -
Sedation 39 - - -
Depression 36 3,950 568 266
Suicidal Ideation 32 3,991 538 300
Weight Increased 32 7,698 1,673 441

"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.

asenapine peer mix vs class inventory

Peer mix

0 OTC and 11 Rx SPL records in this peer set (11 total). Class inventory for Atypical Antipsychotic: 12 drugs.

Frequently Asked Questions

What same-class SPL records sit beside asenapine?
This registry lists 11 Atypical Antipsychotic medication records beside asenapine, including aripiprazole, brexpiprazole, cariprazine, and more. Grouping is therapeutic-class indexing from openFDA/SPL, not a product recommendation.

Reading a wide Atypical Antipsychotic peer set (11 records)

asenapine (Saphris) sits in a wide Atypical Antipsychotic peer set (11 of 11 class peers shown). Labeled indication field for asenapine: Asenapine is used to treat bipolar I disorder.

Top FAERS reaction fields for asenapine total 456 reports across 10 reactions, set beside aripiprazole, brexpiprazole, cariprazine. Counts are exposure-weighted submissions, not per-patient risk.

Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.

Full asenapine profile →

Field note for asenapine: see also the generic vs brand label guide when reading Saphris SPL strings.