FDA Drug Shortage Database
Remifentanil (Ultiva) shortage
The FDA Drug Shortage Database lists 3 of 9 remifentanil presentations as limited or unavailable (updated October 6, 2026); the first entry was posted on June 28, 2022. 6 more presentations are on the list as available.
- Generic listed
- In shortage
- Boxed warning
- DEA Schedule II
Check it at the source: the FDA Drug Shortage Database.
Which strengths are short?
| Strength | Limited or unavailable now | Listed now, available | Resolved or discontinued |
|---|---|---|---|
| 1mg injection | 1 | 0 | 0 |
| 1mg/1ml injection | 1 | 3 | 0 |
| 2mg injection | 1 | 1 | 0 |
| 5mg injection | 0 | 2 | 0 |
Which presentations are listed?
Limited or unavailable now (3)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Remifentanil Hydrochloride, Injection, 1 mg per vial (NDC 0143-9391-10) | Hikma Pharmaceuticals USA, Inc. | Current posted June 28, 2022, updated September 18, 2026 | Unavailable; Demand increase for the drug |
| Remifentanil Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-724-05) | Fresenius Kabi USA, LLC | Current posted June 28, 2022, updated September 15, 2026 | Unavailable; Delay in shipping of the drug |
| Remifentanil Hydrochloride, Injection, 2 mg per vial (NDC 0143-9392-10) | Hikma Pharmaceuticals USA, Inc. | Current posted June 28, 2022, updated September 18, 2026 | Unavailable; Demand increase for the drug |
Listed now, available (6)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Remifentanil Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-723-03) | Fresenius Kabi USA, LLC | Current posted June 28, 2022, updated October 6, 2026 | Available |
| Remifentanil Hydrochloride, Injection, 1 mg/1 mL (NDC 63323-725-10) | Fresenius Kabi USA, LLC | Current posted June 28, 2022, updated October 6, 2026 | Available |
| Remifentanil Hydrochloride, Injection, 5 mg per vial (NDC 0143-9393-10) | Hikma Pharmaceuticals USA, Inc. | Current posted June 28, 2022, updated September 18, 2026 | Available |
| Ultiva, Injection, 1 mg/1 mL (NDC 72078-034-01) | Mylan Institutional, a Viatris Company | Current posted June 28, 2022, updated October 5, 2026 | Available |
| Ultiva, Injection, 2 mg (NDC 72078-035-02) | Mylan Institutional, a Viatris Company | Current posted June 28, 2022, updated October 5, 2026 | Available |
| Ultiva, Injection, 5 mg (NDC 72078-036-05) | Mylan Institutional, a Viatris Company | Current posted June 28, 2022, updated October 5, 2026 | Available |
Source: FDA Drug Shortage Database via openFDA, read October 8, 2026
What next?
- Every shortage now
- medicines by presentations in shortage