FDA Drug Shortage Database
Epinephrine and lidocaine (Xylocaine) shortage
The FDA Drug Shortage Database lists 8 of 10 epinephrine and lidocaine presentations as limited or unavailable (updated September 22, 2026); the first entry was posted on February 22, 2012. 2 more presentations are on the list as available.
- Generic listed
- In shortage
Check it at the source: the FDA Drug Shortage Database.
Which strengths are short?
| Strength | Limited or unavailable now | Listed now, available | Resolved or discontinued |
|---|---|---|---|
| 1g/50ml injection | 1 | 0 | 0 |
| 75mg/5ml injection | 1 | 0 | 0 |
| 200mg/20ml injection | 1 | 0 | 0 |
| 250mg/50ml injection | 1 | 0 | 0 |
| 300mg/30ml injection | 1 | 0 | 0 |
| 400mg/20ml injection | 1 | 1 | 0 |
| 450mg/30ml injection | 0 | 1 | 0 |
| 500mg/50ml injection | 1 | 0 | 0 |
| 600mg/30ml injection | 1 | 0 | 0 |
Which presentations are listed?
Limited or unavailable now (8)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Lidocaine Hydrochloride And Epinephrine, Injection, 1 g/50 mL (2%; 1:100,000) (NDC 0409-3182-03) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Limited Availability; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 200 mg/20 mL (1%; 1:100,000) (NDC 0409-3178-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 250 mg/50 mL (0.5%; 1:200,000) (NDC 0409-3177-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 300 mg/30 mL (1%; 1:100,000) (NDC 0409-3178-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:100,000) (NDC 0409-3182-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 500 mg/50 mL (1%; 1:100,000) (NDC 0409-3178-03) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Limited Availability; Other |
| Lidocaine Hydrochloride And Epinephrine, Injection, 75 mg/5 mL (1.5%; 1:200,000) (NDC 0409-1209-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride and Epinephrine, Injection, 600 mg/30 mL (2%; 1:100,000) (NDC 0409-3182-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Limited Availability; Other |
Listed now, available (2)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:200,000) (NDC 0409-3183-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride And Epinephrine, Injection, 450 mg/30 mL (1.5%; 1:200,000) (NDC 0409-3181-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
Source: FDA Drug Shortage Database via openFDA, read October 8, 2026
What next?
- Every shortage now
- medicines by presentations in shortage