Warfarin · more major-labeled pairs than Allopurinol

SPL labels Warfarin + Allopurinol as minor; Warfarin 133 / Allopurinol 6 in that band.

Mechanism on file: Allopurinol slows down the body's ability to break down warfarin. This can cause warfarin to stay in the body longer and increase the risk of bleeding.

FDA SPL severity: Minor

Warfarin

Full Warfarin label record

Vitamin K Antagonist (Anticoagulant)

Allopurinol

Full Allopurinol label record

Xanthine Oxidase Inhibitor

Warfarin + Allopurinol · SPL mechanism field

Allopurinol slows down the body's ability to break down warfarin. This can cause warfarin to stay in the body longer and increase the risk of bleeding.

Minor band excerpt · Warfarin with Allopurinol

Warfarin Clinical Impact Allopurinol may inhibit the metabolism of warfarin, possibly enhancing its anticoagulant effect. Assess INR frequently and adjust warfarin dosage accordingly when allopurinol is added to warfarin therapy.

Warfarin · 2 major-labeled pairs (vs Allopurinol's 1)

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FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.