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What the FDA labels say about taking them together

Valganciclovir and vincristine

Valganciclovir's FDA label of December 8, 2025 names vincristine in its drug interactions section; the vincristine label PlainMeds reads does not name valganciclovir. The valganciclovir label: “Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.”

Check it at the source: the valganciclovir FDA label on DailyMed (effective December 8, 2025, H2-Pharma, LLC); the vincristine FDA label on DailyMed (effective February 17, 2026, Hospira, Inc.).

What does the valganciclovir label say about vincristine?

Valganciclovir label, drug interactions

Name of the Concomitant Drug: Other drugs associated with myelosuppression or nephrotoxicity (e.g., adriamycin, dapsone, doxorubicin, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/ sulfamethoxazole, vinblastine, vincristine, and zidovudine); Change in the Concentration of Ganciclovir or Concomitant Drug: Unknown; Clinical Comment: Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.

Source: FDA drug label (Valcyte), NDA021304 (Cheplapharm), as published by H2-Pharma, LLC, effective December 8, 2025 (SPL set 4c517a39-2ded-4c5a-8d56-276853414b31), via openFDA; the full label on DailyMed

What does the vincristine label say about valganciclovir?

Vincristine's label (effective February 17, 2026) does not name valganciclovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VinCRIStine Sulfate), Hospira, Inc., effective February 17, 2026 (SPL set b22e4c8e-dbe1-4d4b-a026-e1812974071c), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

19Valganciclovir generic labelers
1Vincristine generic labelers
ValganciclovirVincristine
Labeled forn/aLeukemia, lymphoma and myeloma
Boxed warningYesYes
Pharmacy cost (NADAC)$1.91 per tablet 450 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?